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Microbial metabolism of α-mangostin isolated from Garcinia mangostana L.

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dc.contributor.authorArunrattiyakorn P.
dc.contributor.authorSuksamrarn S.
dc.contributor.authorSuwannasai N.
dc.contributor.authorKanzaki H.
dc.date.accessioned2021-04-05T03:35:19Z
dc.date.available2021-04-05T03:35:19Z
dc.date.issued2011
dc.date.issuedBE2554
dc.description.abstractα-Mangostin (1), a prenylated xanthone isolated from the fruit hull of Garcinia mangostana L., was individually metabolized by two fungi, Colletotrichum gloeosporioides (EYL131) and Neosartorya spathulata (EYR042), repectively. Incubation of 1 with C. gloeosporioides (EYL131) gave four metabolites which were identified as mangostin 3-sulfate (2), mangostanin 6-sulfate (3), 17,18-dihydroxymangostanin 6-sulfate (4)and isomangostanin 3-sulfate (5). Compound 2 was also formed by incubation with N. spathulata (EYR042). The structures of the isolated compounds were elucidated by spectroscopic data analysis. Of the isolated metabolites, 2 exhibited significant anti-mycobacterial activity against Mycobacterium tuberculosis. © 2011 Elsevier Ltd. All rights reserved.
dc.format.mimetypeapplication/pdf
dc.identifier.citationPhytochemistry. Vol 72, No.8 (2011), p.730-734
dc.identifier.doi10.1016/j.phytochem.2011.02.007
dc.identifier.issn319422
dc.identifier.other2-s2.0-79954597523
dc.identifier.urihttps://hdl.handle.net/20.500.14740/7319
dc.rights.holderScopus
dc.subject.otherAntiinfective agent
dc.subject.otherMangostin
dc.subject.otherXanthone derivative
dc.subject.otherArticle
dc.subject.otherChemical structure
dc.subject.otherChemistry
dc.subject.otherGarcinia mangostana
dc.subject.otherIsolation and purification
dc.subject.otherMetabolism
dc.subject.otherMicrobiological examination
dc.subject.otherStereoisomerism
dc.subject.otherAnti-Bacterial Agents
dc.subject.otherGarcinia mangostana
dc.subject.otherMicrobial Sensitivity Tests
dc.subject.otherMolecular Structure
dc.subject.otherStereoisomerism
dc.subject.otherXanthones
dc.subject.otherColletotrichum
dc.subject.otherFungi
dc.subject.otherGarcinia mangostana
dc.subject.otherGlomerella cingulata
dc.subject.otherMycobacterium tuberculosis
dc.subject.otherNeosartorya
dc.subject.otherNeosartorya spathulata
dc.titleMicrobial metabolism of α-mangostin isolated from Garcinia mangostana L.
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79954597523&doi=10.1016%2fj.phytochem.2011.02.007&partnerID=40&md5=d064327319bd37d03baa9d55e46efc80

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