Publication:
Microbial metabolism of α-mangostin isolated from Garcinia mangostana L.

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Issued Date

2011

Resource Type

Article

File Type

application/pdf

ISSN

319422

DOI

10.1016/j.phytochem.2011.02.007

Other identifier(s)

2-s2.0-79954597523

Rights Holder(s)

Scopus

Bibliographic Citation

Phytochemistry. Vol 72, No.8 (2011), p.730-734

Suggested Citation

Arunrattiyakorn P., Suksamrarn S., Suwannasai N., Kanzaki H. Microbial metabolism of α-mangostin isolated from Garcinia mangostana L.. Phytochemistry. Vol 72, No.8 (2011), p.730-734. doi:10.1016/j.phytochem.2011.02.007 Retrieved from: https://hdl.handle.net/20.500.14740/7319

Title

Microbial metabolism of α-mangostin isolated from Garcinia mangostana L.

Author(s)

Arunrattiyakorn P.
 Suksamrarn S.
 Suwannasai N.
 Kanzaki H.

Abstract

α-Mangostin (1), a prenylated xanthone isolated from the fruit hull of Garcinia mangostana L., was individually metabolized by two fungi, Colletotrichum gloeosporioides (EYL131) and Neosartorya spathulata (EYR042), repectively. Incubation of 1 with C. gloeosporioides (EYL131) gave four metabolites which were identified as mangostin 3-sulfate (2), mangostanin 6-sulfate (3), 17,18-dihydroxymangostanin 6-sulfate (4)and isomangostanin 3-sulfate (5). Compound 2 was also formed by incubation with N. spathulata (EYR042). The structures of the isolated compounds were elucidated by spectroscopic data analysis. Of the isolated metabolites, 2 exhibited significant anti-mycobacterial activity against Mycobacterium tuberculosis. © 2011 Elsevier Ltd. All rights reserved.

Subject(s)

Antiinfective agent
 Mangostin
 Xanthone derivative
 Article
 Chemical structure
 Chemistry
 Garcinia mangostana
 Isolation and purification
 Metabolism
 Microbiological examination
 Stereoisomerism
 Anti-Bacterial Agents
 Garcinia mangostana
 Microbial Sensitivity Tests
 Molecular Structure
 Stereoisomerism
 Xanthones
 Colletotrichum
 Fungi
 Garcinia mangostana
 Glomerella cingulata
 Mycobacterium tuberculosis
 Neosartorya
 Neosartorya spathulata

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URI

https://hdl.handle.net/20.500.14740/7319

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Scopus: Year 1983-2021

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