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Selective extraction of cordycepin from Cordyceps militaris–optimisation, kinetics and equilibrium studies

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dc.contributor.authorSornchaithawatwong C.
dc.contributor.authorKunthakudee N.
dc.contributor.authorSunsandee N.
dc.contributor.authorRamakul P.
dc.date.accessioned2022-12-14T03:17:13Z
dc.date.available2022-12-14T03:17:13Z
dc.date.issued2022
dc.date.issuedBE2565
dc.description.abstractCordycepin was separated successfully from Cordyceps militaris using extraction with a mixture of ethanol and water. Optimum temperature, composition of ethanol in water, solvent/solid ratio and pH of solvent were determined by a central composite design (CCD) with respect to extraction yield. The highest yield for cordycepin (96%) was predicted by the regression model and validated by comparison with the experimental results, showing good agreement. The RP-HPLC method was applied to analyse cordycepin from Cordyceps militaris extracts, and 100% purity of cordycepin was achieved. The extraction characteristics were investigated in terms of equilibrium and kinetics. The second-order kinetics correlates well with the experimental data. © 2020 Indian Institute of Chemical Engineers.
dc.format.mimetypeapplication/pdf
dc.identifier.citationJournal of Asthma and Allergy. Vol 15, No. (2022), p.1605-1621
dc.identifier.doi10.1080/00194506.2020.1776163
dc.identifier.issn194506
dc.identifier.urihttps://hdl.handle.net/20.500.14740/9971
dc.language.isoeng
dc.publisherTaylor and Francis Ltd.
dc.rights.holderScopus
dc.subject.otherCordycepin
dc.subject.otherCordyceps militaris
dc.subject.otherExtraction
dc.subject.otherRP-HPLC
dc.titleSelective extraction of cordycepin from Cordyceps militaris–optimisation, kinetics and equilibrium studies
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85086911762&doi=10.1080%2f00194506.2020.1776163&partnerID=40&md5=14dd351d4bed20f08e5386eec640dafd

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