Publication:
Selective extraction of cordycepin from Cordyceps militaris–optimisation, kinetics and equilibrium studies

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Issued Date

2022

Resource Type

Article

Language

eng

File Type

application/pdf

ISSN

194506

DOI

10.1080/00194506.2020.1776163

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of Asthma and Allergy. Vol 15, No. (2022), p.1605-1621

Suggested Citation

Sornchaithawatwong C., Kunthakudee N., Sunsandee N., Ramakul P. Selective extraction of cordycepin from Cordyceps militaris–optimisation, kinetics and equilibrium studies. Journal of Asthma and Allergy. Vol 15, No. (2022), p.1605-1621. doi:10.1080/00194506.2020.1776163 Retrieved from: https://hdl.handle.net/20.500.14740/9971

Title

Selective extraction of cordycepin from Cordyceps militaris–optimisation, kinetics and equilibrium studies

Author(s)

Sornchaithawatwong C.
 Kunthakudee N.
 Sunsandee N.
 Ramakul P.

Abstract

Cordycepin was separated successfully from Cordyceps militaris using extraction with a mixture of ethanol and water. Optimum temperature, composition of ethanol in water, solvent/solid ratio and pH of solvent were determined by a central composite design (CCD) with respect to extraction yield. The highest yield for cordycepin (96%) was predicted by the regression model and validated by comparison with the experimental results, showing good agreement. The RP-HPLC method was applied to analyse cordycepin from Cordyceps militaris extracts, and 100% purity of cordycepin was achieved. The extraction characteristics were investigated in terms of equilibrium and kinetics. The second-order kinetics correlates well with the experimental data. © 2020 Indian Institute of Chemical Engineers.

Subject(s)

Cordycepin
 Cordyceps militaris
 Extraction
 RP-HPLC

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URI

https://hdl.handle.net/20.500.14740/9971

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Scopus: Year 2022

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