Publication: Transparent Cross-Flow Platform as Chemiluminescence Detection Cell in Cross Injection Analysis
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Issued Date
2023
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application/pdf
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Scopus
Bibliographic Citation
Molecules. Vol 28, No.3 (2023)
Suggested Citation
Somboonsuk T., Saetear P., Mantim T., Ratanawimarnwong N., Wilairat P., Choengchan N., Nacapricha D. Transparent Cross-Flow Platform as Chemiluminescence Detection Cell in Cross Injection Analysis. Molecules. Vol 28, No.3 (2023). doi:10.3390/molecules28031316 Retrieved from: https://hdl.handle.net/20.500.14740/12607
Other Contributor(s)
Abstract
This work presents the use of a transparent ‘Cross Injection Analysis’ (CIA) platform as a flow system for chemiluminescence (CL) measurements. The CL-CIA flow device incorporates introduction channels for samples and reagents, and the reaction and detection channels are in one acrylic unit. A photomultiplier tube placed above the reaction channel detects the emitted luminescence. The system was applied to the analysis of (i) Co(II) via the Co(II)-catalyzed H2O2-luminol reaction and (ii) paracetamol via its inhibitory effect on the catalytic activity of Fe(CN)63− on the H2O2-luminol reaction. A linear calibration was obtained for Co(II) in the range of 0.002 to 0.025 mg L−1 Co(II) (r2 = 0.9977) for the determination of Co(II) in water samples. The linear calibration obtained for the paracetamol was 10 to 200 mg L−1 (r2 = 0.9906) for the determination of pharmaceutical products. The sample throughput was 60 samples h−1. The precision was ≤4.2% RSD. The consumption of the samples and reagents was ca. 170 µL per analysis cycle. © 2023 by the authors.