Publication: Iridoids with anti-inflammatory activity from Vitex peduncularis
| dc.contributor.author | Suksamrarn A. | |
| dc.contributor.author | Kumpun S. | |
| dc.contributor.author | Kirtikara K. | |
| dc.contributor.author | Yingyongnarongkul B. | |
| dc.contributor.author | Suksamrarn S. | |
| dc.date.accessioned | 2021-04-05T04:33:06Z | |
| dc.date.available | 2021-04-05T04:33:06Z | |
| dc.date.issued | 2002 | |
| dc.date.issuedBE | 2545 | |
| dc.description.abstract | A new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark. Both pedunculariside and agnuside showed preferential inhibition of COX-2, with IC50 values of 0.15 ± 0.21 mg/ml and 0.026 ± 0.015 mg/ml respectively, while having only small inhibitory effects on COX-1. Both compounds did not exhibit cytotoxicity against vero cells. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.citation | Planta Medica. Vol 68, No.1 (2002), p.72-73 | |
| dc.identifier.doi | 10.1055/s-2002-20048 | |
| dc.identifier.issn | 320943 | |
| dc.identifier.other | 2-s2.0-0036154975 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14740/6738 | |
| dc.rights.holder | มหาวิทยาลัยศรีนครินทรวิโรฒ | |
| dc.subject.other | Agnuside | |
| dc.subject.other | Antiinflammatory agent | |
| dc.subject.other | Cyclooxygenase 2 | |
| dc.subject.other | Iridoid | |
| dc.subject.other | Pedunculariside | |
| dc.subject.other | Plant extract | |
| dc.subject.other | Unclassified drug | |
| dc.subject.other | Vitex peduncularis extract | |
| dc.subject.other | Animal cell | |
| dc.subject.other | Antiinflammatory activity | |
| dc.subject.other | Article | |
| dc.subject.other | Bark | |
| dc.subject.other | Controlled study | |
| dc.subject.other | Cytotoxicity | |
| dc.subject.other | Drug isolation | |
| dc.subject.other | Drug structure | |
| dc.subject.other | Enzyme inhibition | |
| dc.subject.other | IC 50 | |
| dc.subject.other | Nonhuman | |
| dc.subject.other | Vero cell | |
| dc.subject.other | Animals | |
| dc.subject.other | Anti-Inflammatory Agents | |
| dc.subject.other | Cercopithecus aethiops | |
| dc.subject.other | Cyclooxygenase 1 | |
| dc.subject.other | Cyclooxygenase 2 | |
| dc.subject.other | Glucosides | |
| dc.subject.other | Iridoids | |
| dc.subject.other | Isoenzymes | |
| dc.subject.other | Magnetic Resonance Spectroscopy | |
| dc.subject.other | Membrane Proteins | |
| dc.subject.other | Mice | |
| dc.subject.other | Plant Extracts | |
| dc.subject.other | Prostaglandin-Endoperoxide Synthases | |
| dc.subject.other | Pyrans | |
| dc.subject.other | Vero Cells | |
| dc.subject.other | Vitex | |
| dc.subject.other | Animalia | |
| dc.subject.other | Vitex | |
| dc.title | Iridoids with anti-inflammatory activity from Vitex peduncularis | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| swu.datasource.scopus | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036154975&doi=10.1055%2fs-2002-20048&partnerID=40&md5=a1eca6bac96acee5285401d04f3939ef |