Publication:
Quartz crystal microbalance DNA based biosensor for diagnosis: A review

dc.contributor.authorKaewphinit T.
dc.contributor.authorSantiwatanakul S.
dc.contributor.authorChansiri K.
dc.date.accessioned2021-04-05T03:33:55Z
dc.date.available2021-04-05T03:33:55Z
dc.date.issued2012
dc.date.issuedBE2555
dc.description.abstractGenerally, the detection of particular DNA sequence is carried out by gel electrophoresis of DNA fragments amplified by polymerase chain reaction (PCR) using primers which are specific complementary sequence with the chosen region of DNA. Although gel electrophoresis is simple and effective for detection of PCR products, the use of carcinogenic ethidium bromide as a common stain is risky and hazardous. The DNA quartz crystal microbalance (DNA-QCM) lays the groundwork for incorporating the method for rapid DNA analysis. QCM biosensor is an extremely sensitive mass sensor, capable of measuring picogram levels of mass changes. This is a great potential market for simple, cheap, rapid, and quantitative detection of specific genes. QCM requires any non-labeling such as radio isotope, enzyme, and fluorescence tag. © 2012 IFSA.
dc.format.mimetypeapplication/pdf
dc.identifier.citationSensors and Transducers. Vol 143, No.8 (2012), p.44-59
dc.identifier.issn17265479
dc.identifier.other2-s2.0-84866644968
dc.identifier.urihttps://hdl.handle.net/20.500.14740/6956
dc.rights.holderมหาวิทยาลัยศรีนครินทรวิโรฒ
dc.subject.otherComplementary sequences
dc.subject.otherDNA analysis
dc.subject.otherDNA fragment
dc.subject.otherDNA-based biosensors
dc.subject.otherEthidium bromide
dc.subject.otherGel electrophoresis
dc.subject.otherHybridization
dc.subject.otherMass change
dc.subject.otherPCR products
dc.subject.otherPicogram level
dc.subject.otherPotential markets
dc.subject.otherQuantitative detection
dc.subject.otherSensitive mass
dc.subject.otherBiosensors
dc.subject.otherBromine compounds
dc.subject.otherDNA
dc.subject.otherElectrophoresis
dc.subject.otherIsotopes
dc.subject.otherQuartz crystal microbalances
dc.subject.otherRadioactive waste vitrification
dc.subject.otherPolymerase chain reaction
dc.titleQuartz crystal microbalance DNA based biosensor for diagnosis: A review
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84866644968&partnerID=40&md5=3ce8a3cc6e222f96f743fb036d4f9f1c

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