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Home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection

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dc.contributor.authorWongjitrat C.
dc.contributor.authorWongjitrat N.
dc.date.accessioned2021-04-05T03:33:15Z
dc.date.available2021-04-05T03:33:15Z
dc.date.issued2013
dc.date.issuedBE2556
dc.description.abstractObjective: To evaluate the sensitivity and specificity of home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection. Material and Method: A cross-sectional study of patients who underwent esophagogastro- duodenoscopy from June 2009 to May 2010 was carried out. Gastric biopsy specimens were taken from antrum and body of the stomach for home-made rapid urease testing, commercial kit (hpfast) urease testing, and histological study. Results: One hundred and ninety nine patients were included in the present study. The sensitivity of home-made rapid urease test and hpfast were 40% and 48.5% at 1 hour and 91.4% and 91.4% at 24 hours. The specificity, positive and negative predictive value and accuracy of home-made rapid urease test vs. hpfast were 100% vs. 100%, 100% vs. 100%, 95.5% vs. 95.5% and 96.9% vs. 96.9% respectively. Furthermore 45.3% of home-made rapid urease test and 54.7% of hpfast showed positive results within 1 hour. Conclusion: Home-made rapid urease test has good sensitivity and specificity comparable to commercial kit for the diagnosis of H. pylori infection.
dc.format.mimetypeapplication/pdf
dc.identifier.citationJournal of the Medical Association of Thailand. Vol 96, No.SUPPL.1 (2013), p.S96-S100
dc.identifier.issn1252208
dc.identifier.other2-s2.0-84876835123
dc.identifier.urihttps://hdl.handle.net/20.500.14740/6752
dc.rights.holderมหาวิทยาลัยศรีนครินทรวิโรฒ
dc.subject.otherAdult
dc.subject.otherAnemia
dc.subject.otherArticle
dc.subject.otherCross-sectional study
dc.subject.otherDiagnostic accuracy
dc.subject.otherDiagnostic kit
dc.subject.otherDiagnostic test accuracy study
dc.subject.otherDyspepsia
dc.subject.otherEsophagogastroduodenoscopy
dc.subject.otherFemale
dc.subject.otherGastritis
dc.subject.otherGastroesophageal reflux
dc.subject.otherHelicobacter infection
dc.subject.otherHistology
dc.subject.otherHome diagnostic test
dc.subject.otherHuman
dc.subject.otherHuman tissue
dc.subject.otherMajor clinical study
dc.subject.otherMale
dc.subject.otherPredictive value
dc.subject.otherRapid urease test
dc.subject.otherSensitivity and specificity
dc.subject.otherStomach biopsy
dc.subject.otherStomach ulcer
dc.subject.otherUpper gastrointestinal bleeding
dc.subject.otherFemale
dc.subject.otherHelicobacter Infections
dc.subject.otherHelicobacter pylori
dc.subject.otherHumans
dc.subject.otherMale
dc.subject.otherMiddle Aged
dc.subject.otherPredictive Value of Tests
dc.subject.otherReagent Kits, Diagnostic
dc.subject.otherSensitivity and Specificity
dc.subject.otherUrease
dc.titleHome-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection
dc.typeArticle
dspace.entity.typePublication
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