Publication:
Home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection

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Issued Date

2013

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84876835123

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 96, No.SUPPL.1 (2013), p.S96-S100

Suggested Citation

Wongjitrat C., Wongjitrat N. Home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection. Journal of the Medical Association of Thailand. Vol 96, No.SUPPL.1 (2013), p.S96-S100. Retrieved from: https://hdl.handle.net/20.500.14740/6752

Title

Home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection

Author(s)

Wongjitrat C.
 Wongjitrat N.

Abstract

Objective: To evaluate the sensitivity and specificity of home-made rapid urease test compared with commercial kit for diagnosis of Helicobacter pylori infection. Material and Method: A cross-sectional study of patients who underwent esophagogastro- duodenoscopy from June 2009 to May 2010 was carried out. Gastric biopsy specimens were taken from antrum and body of the stomach for home-made rapid urease testing, commercial kit (hpfast) urease testing, and histological study. Results: One hundred and ninety nine patients were included in the present study. The sensitivity of home-made rapid urease test and hpfast were 40% and 48.5% at 1 hour and 91.4% and 91.4% at 24 hours. The specificity, positive and negative predictive value and accuracy of home-made rapid urease test vs. hpfast were 100% vs. 100%, 100% vs. 100%, 95.5% vs. 95.5% and 96.9% vs. 96.9% respectively. Furthermore 45.3% of home-made rapid urease test and 54.7% of hpfast showed positive results within 1 hour. Conclusion: Home-made rapid urease test has good sensitivity and specificity comparable to commercial kit for the diagnosis of H. pylori infection.

Subject(s)

Adult
 Anemia
 Article
 Cross-sectional study
 Diagnostic accuracy
 Diagnostic kit
 Diagnostic test accuracy study
 Dyspepsia
 Esophagogastroduodenoscopy
 Female
 Gastritis
 Gastroesophageal reflux
 Helicobacter infection
 Histology
 Home diagnostic test
 Human
 Human tissue
 Major clinical study
 Male
 Predictive value
 Rapid urease test
 Sensitivity and specificity
 Stomach biopsy
 Stomach ulcer
 Upper gastrointestinal bleeding
 Female
 Helicobacter Infections
 Helicobacter pylori
 Humans
 Male
 Middle Aged
 Predictive Value of Tests
 Reagent Kits, Diagnostic
 Sensitivity and Specificity
 Urease

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URI

https://hdl.handle.net/20.500.14740/6752

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Scopus: Year 1983-2021

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