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Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E

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dc.contributor.authorPrayongratana K.
dc.contributor.authorPolprasert C.
dc.contributor.authorRaungrongmorakot K.
dc.contributor.authorTatone K.
dc.contributor.authorSantiwatanakul S.
dc.date.accessioned2021-04-05T04:31:57Z
dc.date.available2021-04-05T04:31:57Z
dc.date.issued2008
dc.date.issuedBE2551
dc.description.abstractObjective: To evaluate hemoglobin E screening tests in a large scale of cases. Material and Method: A cross-sectional descriptive study was conducted. Whole blood obtained from subjects was evaluated for CBC, OF, DCIP, and hemoglobin typing. Results: Five hundred twenty seven hemoglobin E and 280 reference subjects participated. DCIP's sensitivity, specificity, positive predictive value, and negative predictive value were 97.16%, 98.93%, 99.42%, and 95.19%, respectively. These values of OF were 69.12%, 80.00%, 86.67%, and 57.88%, respectively. In the combination of DCIP and OF gave rise to these values of 99.43%, 79.29%, 90.03%, and 96.67%, respectively. Finally the combination of DCIP and MCV < 80 fL resulted in these values to be 99.43%, 98.93%, 99.43%, and 98.93%, respectively. False positive and false negative rate were 1.07% and 0.57%, respectively. Conclusion: Combination of DCIP and MCV was better than that of DCIP and OF in hemoglobin E screening.
dc.format.mimetypeapplication/pdf
dc.identifier.citationJournal of the Medical Association of Thailand. Vol 91, No.10 (2008), p.1499-1504
dc.identifier.issn1252208
dc.identifier.other2-s2.0-55249125926
dc.identifier.urihttps://hdl.handle.net/20.500.14740/3885
dc.rights.holderScopus
dc.subject.other2,6 dichlorophenolindophenol
dc.subject.otherHemoglobin E
dc.subject.otherAdult
dc.subject.otherArticle
dc.subject.otherDescriptive research
dc.subject.otherFalse negative result
dc.subject.otherFalse positive result
dc.subject.otherFemale
dc.subject.otherHuman
dc.subject.otherMajor clinical study
dc.subject.otherMale
dc.subject.otherMean corpuscular volume
dc.subject.otherOsmotic fragility
dc.subject.otherScreening
dc.subject.otherSensitivity and specificity
dc.subject.other2,6-Dichloroindophenol
dc.subject.otherAdult
dc.subject.otherCross-Sectional Studies
dc.subject.otherErythrocyte Indices
dc.subject.otherFemale
dc.subject.otherHemoglobin E
dc.subject.otherHumans
dc.subject.otherMale
dc.subject.otherMass Screening
dc.subject.otherOsmotic Fragility
dc.subject.otherPredictive Value of Tests
dc.subject.otherSensitivity and Specificity
dc.subject.otherThalassemia
dc.titleLow cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-55249125926&partnerID=40&md5=809907043b391a58fc7429c02729ed38

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