Publication:
Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E

0
0

Issued Date

2008

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-55249125926

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 91, No.10 (2008), p.1499-1504

Suggested Citation

Prayongratana K., Polprasert C., Raungrongmorakot K., Tatone K., Santiwatanakul S. Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E. Journal of the Medical Association of Thailand. Vol 91, No.10 (2008), p.1499-1504. Retrieved from: https://hdl.handle.net/20.500.14740/3885

Title

Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E

Author(s)

Prayongratana K.
 Polprasert C.
 Raungrongmorakot K.
 Tatone K.
 Santiwatanakul S.

Abstract

Objective: To evaluate hemoglobin E screening tests in a large scale of cases. Material and Method: A cross-sectional descriptive study was conducted. Whole blood obtained from subjects was evaluated for CBC, OF, DCIP, and hemoglobin typing. Results: Five hundred twenty seven hemoglobin E and 280 reference subjects participated. DCIP's sensitivity, specificity, positive predictive value, and negative predictive value were 97.16%, 98.93%, 99.42%, and 95.19%, respectively. These values of OF were 69.12%, 80.00%, 86.67%, and 57.88%, respectively. In the combination of DCIP and OF gave rise to these values of 99.43%, 79.29%, 90.03%, and 96.67%, respectively. Finally the combination of DCIP and MCV < 80 fL resulted in these values to be 99.43%, 98.93%, 99.43%, and 98.93%, respectively. False positive and false negative rate were 1.07% and 0.57%, respectively. Conclusion: Combination of DCIP and MCV was better than that of DCIP and OF in hemoglobin E screening.

Subject(s)

2,6 dichlorophenolindophenol
 Hemoglobin E
 Adult
 Article
 Descriptive research
 False negative result
 False positive result
 Female
 Human
 Major clinical study
 Male
 Mean corpuscular volume
 Osmotic fragility
 Screening
 Sensitivity and specificity
 2,6-Dichloroindophenol
 Adult
 Cross-Sectional Studies
 Erythrocyte Indices
 Female
 Hemoglobin E
 Humans
 Male
 Mass Screening
 Osmotic Fragility
 Predictive Value of Tests
 Sensitivity and Specificity
 Thalassemia

View online Resources

Research Projects

Organizational Units

Journal Issue

URI

https://hdl.handle.net/20.500.14740/3885

Collections

Scopus: Year 1983-2021

Endorsement

Review

Supplemented By

Referenced By