Publication:
Association between serum uric acid level and microalbuminuria to chronic vascular complications in Thai patients with type 2 diabetes

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Issued Date

2014

Resource Type

Article

File Type

application/pdf

ISSN

10568727

DOI

10.1016/j.jdiacomp.2013.12.002

Other identifier(s)

2-s2.0-84896727627

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Journal of Diabetes and its Complications. Vol 28, No.2 (2014), p.124-129

Suggested Citation

Chuengsamarn S., Rattanamongkolgul S., Jirawatnotai S. Association between serum uric acid level and microalbuminuria to chronic vascular complications in Thai patients with type 2 diabetes. Journal of Diabetes and its Complications. Vol 28, No.2 (2014), p.124-129. doi:10.1016/j.jdiacomp.2013.12.002 Retrieved from: https://hdl.handle.net/20.500.14740/6983

Title

Association between serum uric acid level and microalbuminuria to chronic vascular complications in Thai patients with type 2 diabetes

Author(s)

Chuengsamarn S.
 Rattanamongkolgul S.
 Jirawatnotai S.

Abstract

Aims To investigate an association between serum uric acid/microalbuminuria and chronic micro/macro-vascular complications in type 2 diabetic patients. Methods This cross-sectional study enrolled 608 patients with type 2 diabetes. All subjects were examined and basic information on health of the subjects was recorded for inclusion criteria. Several chemical parameters (fasting plasma glucose, triglyceride, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, uric acid, and microalbuminuria), and related chronic vascular complications were measured and recorded in data forms. Results Logistic regressions were used to analyse odds ratios between uric acid/microalbuminuria levels and several chronic vascular complications. Prevalence of chronic vascular complications in T2DM patients, namely coronary arterial disease, cerebrovascular disease, diabetic nephropathy, diabetic retinopathy, and diabetic peripheral neuropathy was significantly correlated with increase of uric acid level [2.29 (1.01-5.2), 16.01 (4.74-54.09), 9.99 (4.4-22.8), 4.43 (1.3-15.1), 4.37 (1.5-12.9)], and of microalbuminuria level [7.0 (3.6-13.8), 3.2 (1.2-8.7), NA, 14.7 (5.1-42.7), 7.2 (2.9-17.7)]. Conclusion Both elevated uric acid and microalbuminuria levels were significantly associated with diabetic chronic micro/macro-vascular complications. Monitoring of uric acid and microalbuminuria levels provides a predictive value for a presence of chronic micro/macro-vascular complications in patients with type 2 diabetes. © 2014 Elsevier Inc. All rights reserved.

Subject(s)

Cholesterol
 Glucose
 High density lipoprotein cholesterol
 Low density lipoprotein cholesterol
 Triacylglycerol
 Uric acid
 Adult
 Artery disease
 Article
 Cerebrovascular disease
 Cholesterol blood level
 Cross-sectional study
 Diabetic nephropathy
 Diabetic neuropathy
 Diabetic retinopathy
 Disease association
 Female
 Glucose blood level
 Human
 Lipoprotein blood level
 Macrovascular disease
 Major clinical study
 Male
 Microalbuminuria
 Microangiopathy
 Middle aged
 Non insulin dependent diabetes mellitus
 Priority journal
 Triacylglycerol blood level
 Uric acid blood level
 Vascular disease
 Chronic vascular complications
 Microalbuminuria
 Type 2 diabetes
 Uric acid
 Adult
 Aged
 Albuminuria
 Chronic Disease
 Cross-Sectional Studies
 Diabetes Mellitus, Type 2
 Diabetic Angiopathies
 Female
 Humans
 Male
 Middle Aged
 Thailand
 Uric Acid

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URI

https://hdl.handle.net/20.500.14740/6983

Collections

Scopus: Year 1983-2021

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