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Neuritogenic and neuroprotective activities of the essential oil from rhizomes of curcuma alismatifolia

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dc.contributor.authorKochaphum S.
dc.contributor.authorBanyat P.
dc.contributor.authorTadtong S.
dc.contributor.authorSareedenchai V.
dc.contributor.authorAthikomkulchai S.
dc.date.accessioned2021-04-05T03:04:01Z
dc.date.available2021-04-05T03:04:01Z
dc.date.issued2019
dc.date.issuedBE2562
dc.description.abstractThe essential oil from rhizomes of Curcuma alismatifolia Gagnep. was extracted by hydrodistillation. Chemical analysis by gas chromatography- mass spectrometry identified 12 compounds, of which the most prominent were xanthorrhizol (82.2%), ar-curcumene (6.5%), α-cedrene (1.8%), and β-bisabolol (1.1%). The essential oil at 1 ng/mL showed neuroprotective and neuritogenic activity on P19-derived neurons by significantly enhancing cell viability, length, and branching numbers of the cultured P19-derived neurons. In addition, xanthorrhizol, the major compound of the essential oil, at 10 ng/mL also exhibited the protection of P19-derived neurons. However, the mechanism of their neuroprotective activity was not correlated with their antioxidant activity. © The Author(s) 2019.
dc.format.mimetypeapplication/pdf
dc.identifier.citationNatural Product Communications. Vol 14, No.7 (2019)
dc.identifier.doi10.1177/1934578X19864217
dc.identifier.issn1934578X
dc.identifier.other2-s2.0-85069655022
dc.identifier.urihttps://hdl.handle.net/20.500.14740/5526
dc.rights.holderScopus
dc.subject.otherAlpha bergamotene
dc.subject.otherAlpha cedrene
dc.subject.otherAr curcumene
dc.subject.otherAscorbic acid
dc.subject.otherBeta bisabolol
dc.subject.otherBeta farnesene
dc.subject.otherBisabolol
dc.subject.otherCamphene
dc.subject.otherCamphor
dc.subject.otherCineole
dc.subject.otherEssential oil
dc.subject.otherGamma curcumene
dc.subject.otherPinene
dc.subject.otherQuercetin
dc.subject.otherUnclassified drug
dc.subject.otherXanthorrhizol
dc.subject.otherArticle
dc.subject.otherCell viability
dc.subject.otherControlled study
dc.subject.otherCurcuma
dc.subject.otherCurcuma alismatifolia
dc.subject.otherDrug activity
dc.subject.otherDrug identification
dc.subject.otherHydrodistillation
dc.subject.otherMass fragmentography
dc.subject.otherNerve cell culture
dc.subject.otherNeuritogenic activity
dc.subject.otherNeuroprotection
dc.subject.otherRhizome
dc.titleNeuritogenic and neuroprotective activities of the essential oil from rhizomes of curcuma alismatifolia
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85069655022&doi=10.1177%2f1934578X19864217&partnerID=40&md5=de8d121c6e97edb239eaaa5f079b2705

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