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Kaempferia parviflora ethanolic extract promoted nitric oxide production in human umbilical vein endothelial cells

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dc.contributor.authorWattanapitayakul S.K.
dc.contributor.authorSuwatronnakorn M.
dc.contributor.authorChularojmontri L.
dc.contributor.authorHerunsalee A.
dc.contributor.authorNiumsakul S.
dc.contributor.authorCharuchongkolwongse S.
dc.contributor.authorChansuvanich N.
dc.date.accessioned2021-04-05T04:32:11Z
dc.date.available2021-04-05T04:32:11Z
dc.date.issued2007
dc.date.issuedBE2550
dc.description.abstractThe rhizomes of Kaempferia parviflora (KP) (Zingiberaceae) have been used in Thai traditional medicine for health promotion and for the treatment of digestive disorders and gastric ulcer. This study investigated effect of KP on endothelial function. Studies in human umbilical vein endothelial cells (HUVEC) showed that KP dose-dependently increased nitrite concentrations in culture media after 48 h incubation. eNOS mRNA and protein expression were also enhanced. The induction of eNOS mRNA was detected at 4 h and plateau at 48 h while iNOS expression was not observed. These data demonstrate that KP has a great potential for a supplemental use in vascular endothelial health promotion. © 2006 Elsevier Ireland Ltd. All rights reserved.
dc.format.mimetypeapplication/pdf
dc.identifier.citationJournal of Ethnopharmacology. Vol 110, No.3 (2007), p.559-562
dc.identifier.doi10.1016/j.jep.2006.09.037
dc.identifier.issn3788741
dc.identifier.other2-s2.0-33947122236
dc.identifier.urihttps://hdl.handle.net/20.500.14740/4688
dc.rights.holderScopus
dc.subject.otherAlcohol
dc.subject.otherEndothelial nitric oxide synthase
dc.subject.otherKaempferia parviflora extract
dc.subject.otherMessenger RNA
dc.subject.otherNitric oxide
dc.subject.otherNitrite
dc.subject.otherPlant extract
dc.subject.otherUnclassified drug
dc.subject.otherArticle
dc.subject.otherConcentration response
dc.subject.otherControlled study
dc.subject.otherEndothelium cell
dc.subject.otherGastrointestinal disease
dc.subject.otherGene expression
dc.subject.otherGene induction
dc.subject.otherHealth promotion
dc.subject.otherHuman
dc.subject.otherHuman cell
dc.subject.otherKaempferia parviflora
dc.subject.otherMedicinal plant
dc.subject.otherNonhuman
dc.subject.otherNucleotide sequence
dc.subject.otherProtein expression
dc.subject.otherRhizome
dc.subject.otherStomach ulcer
dc.subject.otherTraditional medicine
dc.subject.otherVascular endothelium
dc.subject.otherZingiberaceae
dc.subject.otherDose-Response Relationship, Drug
dc.subject.otherEndothelial Cells
dc.subject.otherGene Expression Regulation
dc.subject.otherHumans
dc.subject.otherMedicine, Oriental Traditional
dc.subject.otherNitric Oxide
dc.subject.otherNitric Oxide Synthase Type II
dc.subject.otherNitric Oxide Synthase Type III
dc.subject.otherNitrites
dc.subject.otherPhytotherapy
dc.subject.otherPlant Extracts
dc.subject.otherPlants, Medicinal
dc.subject.otherRhizome
dc.subject.otherRNA, Messenger
dc.subject.otherThailand
dc.subject.otherUmbilical Veins
dc.subject.otherZingiberaceae
dc.subject.otherKaempferia parviflora
dc.subject.otherZingiberaceae
dc.titleKaempferia parviflora ethanolic extract promoted nitric oxide production in human umbilical vein endothelial cells
dc.typeArticle
dspace.entity.typePublication
swu.datasource.scopushttps://www.scopus.com/inward/record.uri?eid=2-s2.0-33947122236&doi=10.1016%2fj.jep.2006.09.037&partnerID=40&md5=4b8589f68d1c72d28db3f942fc5e21a8

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