Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/27530
ชื่อเรื่อง: Scalp-mounted Electrical Impedance Tomography of Cerebral Hemodynamics
ผู้แต่ง: Ouypornkochagorn T.
Terzija N.
Wright P.
Davidson J.L.
Polydorides N.
McCann H.
วันที่เผยแพร่: 2022
บทคัดย่อ: An Electrical Impedance Tomography (EIT) system has been developed for dynamic three-dimensional imaging of changes in conductivity distribution in the human head, using scalp-mounted electrodes. We attribute these images to changes in cerebral perfusion. At 100 frames per second (fps), voltage measurement is achieved with full-scale signal-to-noise ratio of 105 dB and common-mode rejection ratio > 90 dB. A novel nonlinear method is presented for 3-D imaging of the difference in conductivity distribution in the head, relative to a reference time. The method achieves much reduced modelling error. It successfully localizes conductivity inclusions in experimental and simulation tests, where previous methods fail. For > 50 human volunteers, the rheoencephalography (REG) waveform is observed in EIT voltage measurements for every volunteer, with peak-to-peak amplitudes up to approx. 50 μVrms. Images are presented of the change in conductivity distribution during the REG/cardiac cycle, at 50 fps, showing maximum local conductivity change of approx. 1% in grey/white matter. A total of 17 tests were performed during short (typically 5s) carotid artery occlusions on 5 volunteers, monitored by Transcranial Doppler ultrasound. From EIT measurements averaged over complete REG/cardiac cycles, 13 occlusion tests showed consistently decreased conductivity of cerebral regions on the occluded side, and increased conductivity on the opposite side. The maximum local conductivity change during occlusion was approx. 20%. The simplicity of the carotid artery intervention provides a striking validation of the scalp-mounted measurement system in imaging cerebral hemodynamics, and the REG images indicate its unique combination of sensitivity and temporal resolution. Author
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123690627&doi=10.1109%2fJSEN.2022.3145587&partnerID=40&md5=0e4fa99c9d51056fba071ec6cd73ae58
https://ir.swu.ac.th/jspui/handle/123456789/27530
ISSN: 1530437X
Appears in Collections:Scopus 2022

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