Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/27290
ชื่อเรื่อง: One-Pot and Green Preparation of Phyllanthus emblica Extract/Silver Nanoparticles/Polyvinylpyrrolidone Spray-On Dressing
ผู้แต่ง: Suvandee W.
Teeranachaideekul V.
Jeenduang N.
Nooeaid P.
Makarasen A.
Chuenchom L.
Techasakul S.
Dechtrirat D.
Keywords: green synthesis
Phyllanthus emblica
silver nanoparticle
spray-on dressing
wound healing
วันที่เผยแพร่: 2022
สำนักพิมพ์: MDPI
บทคัดย่อ: A spray-on wound dressing has many benefits, including easy and quick administration to broad and uneven wounds, better interface with the wound site, adhesion without additional dressing, and multiple applications in a portable package. By limiting direct contact with the wound site, such a design can prevent wound damage during treatment. This study revealed a simple, one-pot synthesis of spray-on wound dressing relying on polyvinylpyrrolidone solution incorporating silver nanoparticles as a broad-spectrum antibacterial agent and wound-healing antioxidant Phyllanthus emblica extract. Silver nanoparticles were synthesized in situ using Phyllanthus emblica extract as a biogenic reducing agent. Polyvinylpyrrolidone was employed as a film-forming agent to create an adhesive hydrogel-based dressing matrix to provide moisture and establish a shielding barrier for the wound bed as well as to regulate the release of fruit extract. In vitro tests revealed that the produced dressing film had a controlled release of the fruit extract, high antioxidant activity, and a good antibacterial action against S. aureus, P. aeruginosa, E. coli, and MRSA. Additionally, a biocompatibility study has shown that both human fibroblasts and keratinocytes are unaffected by the dressing film. Based on established findings, the current spray-on solution might be a potential option for antibacterial wound dressing. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85131375656&doi=10.3390%2fpolym14112205&partnerID=40&md5=be65d9b81203b77fa32bc7a5b9cc7810
https://ir.swu.ac.th/jspui/handle/123456789/27290
ISSN: 20734360
Appears in Collections:Scopus 2022

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.