Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/27104
ชื่อเรื่อง: Diagnostic performance of anterior segment optical coherence tomography in detecting plateau iris
ผู้แต่ง: Wanichwecharungruang B.
Pattanapongpaiboon W.
Kongsomboon K.
Parivisutt N.
Annopawong K.
Seresirikachorn K.
Keywords: Angle
Ciliary body
Diagnostic tests/Investigation
Glaucoma
Imaging
วันที่เผยแพร่: 2022
สำนักพิมพ์: BMJ Publishing Group
บทคัดย่อ: Objective To evaluate the diagnostic performance of manual grading of anterior segment optical coherence tomography (AS-OCT) in detection of plateau iris configuration (PIC) based on the presence of standardised ultrasound biomicroscopy (UBM) criteria in at least two quadrants; namely, clinical diagnosis of PIC (DxPIC). Methods and analysis In this cross-sectional study, paired AS-OCT and UBM images were evaluated by three glaucoma specialists. AS-OCT was classified into two mechanisms, PIC versus non-PIC, of primary angle closure disease (PACD) and AS-OCT-PIC diagnostic performance was tested with DxPIC. Results One hundred and seventy-nine eyes of 142 patients were enrolled for analysis, and DxPIC was found in 85 eyes (47.49%). Intraobserver agreement rates of AS-OCT classification by the graders were 0.77, 0.701 and 0.742 (all p<0.001), and interobserver agreement rates, between a senior glaucoma specialist and the other two glaucoma specialists, were 0.68 and 0.702 (all p<0.001). Plateau iris was classified in AS-OCT images by the three graders, rated 32.96%-39.1% and 24.58%-34.08% in the horizontal and vertical axes, respectively. Diagnostic performance was analysed, yielding sensitivity ranging from 56.47% to 77.78%, and specificity of 48.94% to 64.29%. We applied disease prevalence of 30%, revealing positive predictive values varying from 32.16% to 44.44%, and negative predictive values of 72.4% to 85.71%. Accuracy ranged from 51.2% to 65%. Agreement between the two devices was fair, kappa range 0.31-0.351. Conclusion Performance of manual grading of AS-OCT in detection of DxPIC was relatively poor; therefore, unadjusted AS-OCT does not appear to be good for manual PIC screening in PACD patients and cannot serve as a substitute for UBM in PIC detection. © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127574592&doi=10.1136%2fbmjophth-2021-000931&partnerID=40&md5=181a13dabf70b600ae3af561cd4695bf
https://ir.swu.ac.th/jspui/handle/123456789/27104
ISSN: 23973269
Appears in Collections:Scopus 2022

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.