Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/15440
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dc.contributor.authorUdompataikul M.
dc.contributor.authorSripiroj P.
dc.contributor.authorPalungwachira P.
dc.date.accessioned2021-04-05T04:34:08Z-
dc.date.available2021-04-05T04:34:08Z-
dc.date.issued2009
dc.identifier.issn1425463
dc.identifier.other2-s2.0-70350128005
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-70350128005&doi=10.1111%2fj.1468-2494.2009.00513.x&partnerID=40&md5=33fa5f0ed6f6c320a8e9913aad5b98d3
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/15440-
dc.description.abstractSynopsis Various nutraceuticals (dietary supplements) are claimed to have cutaneous antiageing properties, however, there are a limited number of research studies supporting these claims. The objective of this research was to study the effectiveness of an oral nutraceutical containing antioxidants, minerals and glycosaminoglycans on cutaneous ageing. In this double-blind, placebo-controlled trial, 60 women aged 35-60 years were randomized to receive oral dietary supplement (n = 30) or placebo (n = 30), once daily for 12 weeks. The depth of skin roughness and fine wrinkles were measured using surface evaluation of skin parameters for living skin (Visioscan) at baseline, and at the 4, 8 and 12 weeks of treatment. Surface evaluation using a replica film (Visiometer) at baseline and at the 12th week of treatment was also carried out. Statistical differences in objective skin improvement were assessed by the independent t-test. The volunteers' satisfaction was tested using the chi-squared test. The baseline depth of skin roughness and fine wrinkles in the treatment group and the placebo group were 100.5 and 100 μm, respectively. At the end of the study, the depth of skin roughness and fine wrinkles in the treatment group showed a 21.2% improvement, whereas improvement in the control group was 1.7%. This difference was statistically significant (P < 0.001). With regard to the volunteers' satisfaction, there was no statistically significant decrease in the homogenization of skin colour, however, a statistically significant reduction in pore size and depth of skin roughness and fine wrinkles were observed (P < 0.05). No side effects were noted throughout the study. The oral dietary supplement containing antioxidants, minerals and glycosaminoglycans improved skin roughness and fine wrinkles but did not affect skin colour change in female volunteers. © 2009 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
dc.subjectantioxidant
dc.subjectglycosaminoglycan
dc.subjectmineral
dc.subjectnutraceutical
dc.subjectplacebo
dc.subjectradiance marine q10
dc.subjectunclassified drug
dc.subjectabsence of side effects
dc.subjectadult
dc.subjectarticle
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectcutaneous parameters
dc.subjectdiet supplementation
dc.subjectdouble blind procedure
dc.subjectdrug efficacy
dc.subjectevaluation
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectpatient satisfaction
dc.subjectrandomized controlled trial
dc.subjectskin color
dc.subjectsurface property
dc.subjecttreatment response
dc.subjectwrinkle
dc.subjectAdministration, Oral
dc.subjectAdult
dc.subjectAntioxidants
dc.subjectConsumer Satisfaction
dc.subjectDietary Supplements
dc.subjectDouble-Blind Method
dc.subjectFemale
dc.subjectGlycosaminoglycans
dc.subjectHumans
dc.subjectMiddle Aged
dc.subjectMinerals
dc.subjectQuestionnaires
dc.subjectSkin Aging
dc.subjectSurface Properties
dc.subjectUbiquinone
dc.titleAn oral nutraceutical containing antioxidants, minerals and glycosaminoglycans improves skin roughness and fine wrinkles
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationInternational Journal of Cosmetic Science. Vol 31, No.6 (2009), p.427-435
dc.identifier.doi10.1111/j.1468-2494.2009.00513.x
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