Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15267
ชื่อเรื่อง: Evaluation of Roche Abuscreen ONLINE amphetamine immunoassay for screening of new amphetamine analogues
ผู้แต่ง: Lekskulchai V.
Chintana M.
Keywords: 3,4 methylenedioxyamphetamine
3,4 methylenedioxymethamphetamine
amphetamine derivative
methamphetamine
n ethyl 3,4 methylenedioxyamphetamine
n ethylamphetamine
reagent
article
cross reaction
diagnostic value
drug abuse
drug determination
drug metabolism
human
immunoassay
Thailand
วันที่เผยแพร่: 2001
บทคัดย่อ: Some structural analogues of amphetamine are now important drugs of abuse in Thailand. The utility of the Roche Abuscreen ONLINE reagent amphetamine immunoassay test kit to detect these analogues was studied. The test showed high cross-reactivity to 3,4-methylenedioxyamphetamine (MDA), but low cross-reactivity to its parent drugs, 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyethylamphetamine (MDEA), as well as to methamphetamine and ethylamphetamine. Also observed in this study was a methamphetamine detection sensitivity enhancement effect of amphetamine, which is the active metabolite of methamphetamine. Correlation between the measured concentration values and the actual amount of these two drugs in the sample was, however, low. Thus, the test can be used to detect methamphetamine only when amphetamine is also present in the sample resulting from either co-administration or metabolism of methamphetamine.
URI: https://ir.swu.ac.th/jspui/handle/123456789/15267
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034872340&doi=10.1093%2fjat%2f25.6.471&partnerID=40&md5=49972941842440087f6b3c97b536f3b3
ISSN: 1464760
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.