Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15177
ชื่อเรื่อง: Antimycobacterial and antioxidant flavones from Limnophila geoffrayi
ผู้แต่ง: Suksamrarn A.
Poomsing P.
Aroonrerk N.
Punjanon T.
Suksamrarn S.
Kongkun S.
Keywords: antiinfective agent
antioxidant
chloroform
flavone derivative
flavonoid
isothymusin
nevadensin
plant extract
article
Bacillus subtilis
chemical structure
chemistry
drug effect
genetics
isolation and purification
methodology
microbiological examination
mutagen testing
Mycobacterium tuberculosis
physiology
plant leaf
plant stem
Scrophulariaceae
Anti-Bacterial Agents
Antioxidants
Bacillus subtilis
Chloroform
Flavones
Flavonoids
Microbial Sensitivity Tests
Molecular Structure
Mutagenicity Tests
Mycobacterium tuberculosis
Plant Extracts
Plant Leaves
Plant Stems
Scrophulariaceae
วันที่เผยแพร่: 2003
บทคัดย่อ: The chloroform extract of the aerial part of Limnophila geoffrayi showed antimycobacterial and antioxidant activities. Bioassay-guided fractionation has led to the isolation of the flavones nevadensin (5,7-dihydroxy-6,8,4′- trimethoxyflavone, 1) and isothymusin (6,7-dimethoxy-5,8,4′- trihydroxyflavone, 2). Both compounds 1 and 2 exhibited inhibition activity against Mycobacterium tuberculosis, with equal MIC value of 200 mg/mL. Only compound 2 exhibited antioxidant activity against the radical scavenging ability of DPPH, with the IC50 value of 7.7 μg/mL. The crude hexane, chloroform and methanol extracts as well as the pure compounds 1 and 2 did not exhibit mutagenic activity in the Bacillus subtilis recassay.
URI: https://ir.swu.ac.th/jspui/handle/123456789/15177
https://www.scopus.com/inward/record.uri?eid=2-s2.0-23844456380&doi=10.1007%2fBF02980026&partnerID=40&md5=27d205feb26d9d8f603dede49430a0d1
ISSN: 2536269
Appears in Collections:Scopus 1983-2021

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