Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/14952
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dc.contributor.authorTrisomboon H.
dc.contributor.authorWatanabe G.
dc.contributor.authorWetchasit P.
dc.contributor.authorTaya K.
dc.date.accessioned2021-04-05T04:32:12Z-
dc.date.available2021-04-05T04:32:12Z-
dc.date.issued2007
dc.identifier.issn9168818
dc.identifier.other2-s2.0-34248340060
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-34248340060&doi=10.1262%2fjrd.18092&partnerID=40&md5=d057d6171658762f518aaf6a95ea4f3a
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/14952-
dc.description.abstractThe aim of the present study was to investigate the testosterone-like effect of Kaempferia parviflora (KP). Castrated immature rats were randomized and divided into two groups (control and KP-treatment groups). The rats (n=7-8) were treated daily for 5 days by oral route with water in the control group and 1,000 mg/kg of KP in the treatment group. All rats were decapitated 24 h after their last dose and then blood samples were collected for assay of serum FSH, LH, testosterone, progesterone and corticosterone levels. The seminal vesicles plus coagulating glands, ventral prostate, levator ani muscle plus bulbocavernosus muscle, glans penis, kidneys and the adrenal glands were collected and weighed for organ wet weight. Body weight and weight of food intake were recorded throughout the study period. The results show that relative body weight gain in the KP-treatment group was significantly increased 24 and 48 h after the first dose (P<0.05) and then was indistinguishable from the control group. There were no significant differences in the relative reproductive and non-reproductive organ weights between the groups, although all organ weights, except for the glans penis, tended to increase in the KP-treatment group. The serum testosterone levels were significantly increased in the KP-treatment group. There were no significant differences in the serum FSH, LH, progesterone, or corticosterone levels between the groups, even though the serum progesterone level tended to increase and serum LH level tended to decrease in the KP-treatment group. The present study indicates that KP has no testosterone-like effect on reproduction in male rats.
dc.subjectcorticosterone
dc.subjectfollitropin
dc.subjectluteinizing hormone
dc.subjectplant extract
dc.subjectprogesterone
dc.subjecttestosterone
dc.subjectanimal
dc.subjectarticle
dc.subjectbioassay
dc.subjectblood
dc.subjectbody weight
dc.subjectdose response
dc.subjectdrug effect
dc.subjecteating
dc.subjectmale
dc.subjectmale genital system
dc.subjectmedicinal plant
dc.subjectmethodology
dc.subjectorchiectomy
dc.subjectorgan size
dc.subjectrat
dc.subjectThailand
dc.subjectWistar rat
dc.subjectZingiberaceae
dc.subjectAnimals
dc.subjectBiological Assay
dc.subjectBody Weight
dc.subjectCorticosterone
dc.subjectDose-Response Relationship, Drug
dc.subjectEating
dc.subjectFollicle Stimulating Hormone
dc.subjectGenitalia, Male
dc.subjectLuteinizing Hormone
dc.subjectMale
dc.subjectOrchiectomy
dc.subjectOrgan Size
dc.subjectPlant Extracts
dc.subjectPlants, Medicinal
dc.subjectProgesterone
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectTestosterone
dc.subjectThailand
dc.subjectZingiberaceae
dc.subjectGlans
dc.subjectKaempferia parviflora
dc.subjectRattus
dc.titleEffect of daily treatment with Thai herb, Kaempferia parviflora, in Hershberger assay using castrated immature rats
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationJournal of Reproduction and Development. Vol 53, No.2 (2007), p.351-356
dc.identifier.doi10.1262/jrd.18092
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