Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/14833
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dc.contributor.authorTrisomboon H.
dc.contributor.authorTohei A.
dc.contributor.authorMalaivijitnond S.
dc.contributor.authorWatanabe G.
dc.contributor.authorTaya K.
dc.date.accessioned2021-04-05T04:31:57Z-
dc.date.available2021-04-05T04:31:57Z-
dc.date.issued2008
dc.identifier.issn9168818
dc.identifier.other2-s2.0-55849098119
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-55849098119&doi=10.1262%2fjrd.20028&partnerID=40&md5=44f4f7e7a2270b6957a65a134cf05690
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/14833-
dc.description.abstractTo investigate the androgenic effect of Kaempferia parviflora (KP), a Thai herbal plant, adult male rats were randomized into control and KP-treatment groups. Rats were treated orally with water in the control group and with 1,000 mg/kg/day of KP in the treatment group for 45 days. Blood samples were collected on days 10, 20, 30 and 45 for measurement of the serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, progesterone and corticosterone levels. The reproductive and non-reproductive organs were dissected on day 45 and weighed. Mating behavior was also observed on days 20 and 30. Body weight was measured throughout the study period. The results showed that KP induced an increase in body weight compared with the controls. There were no significant differences in the weights of either reproductive (testis, seminal vesicle plus coagulating gland, levator ani muscle plus bulbocarvernosus muscle and glans penis, except the prostate gland) or non-reproductive organs (kidney, adrenal gland and gastracnemius muscle). There were no significant differences in serum levels of either FSH or LH between the two groups. The serum testosterone and progesterone levels were insignificantly lower in the KP group during the first 30 days. The serum corticosterone levels in the KP group were lower than those in the controls throughout the study period and were significantly low on days 20 and 30. There were no significant changes in mating behavior in the rats treated with KP. Although KP affected the body weight and serum corticosterone level, it did not affect mating behavior, reproductive and non-reproductive organ weights or hormones related to the reproductive system in the adult male rats. Therefore, we conclude that the testosterone-like effect of KP did not disturb the hypothalamic-pituitary-testicular axis or male reproduction.
dc.subjectfollitropin
dc.subjectluteinizing hormone
dc.subjectplant extract
dc.subjectanimal
dc.subjectarticle
dc.subjectblood
dc.subjectbody weight
dc.subjectchemistry
dc.subjectcomparative study
dc.subjectdrug effect
dc.subjecteating
dc.subjectevaluation
dc.subjectmale
dc.subjectoral drug administration
dc.subjectorgan size
dc.subjectplant root
dc.subjectrandomization
dc.subjectrat
dc.subjectreproduction
dc.subjectsexual behavior
dc.subjectWistar rat
dc.subjectZingiberaceae
dc.subjectAdministration, Oral
dc.subjectAnimals
dc.subjectBody Weight
dc.subjectEating
dc.subjectFollicle Stimulating Hormone
dc.subjectLuteinizing Hormone
dc.subjectMale
dc.subjectOrgan Size
dc.subjectPlant Extracts
dc.subjectPlant Roots
dc.subjectRandom Allocation
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectReproduction
dc.subjectSexual Behavior, Animal
dc.subjectZingiberaceae
dc.subjectGlans
dc.subjectKaempferia parviflora
dc.subjectRattus
dc.titleOral administration of Kaempferia parviflora did not disturb male reproduction in rats
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationJournal of Reproduction and Development. Vol 54, No.5 (2008), p.375-380
dc.identifier.doi10.1262/jrd.20028
Appears in Collections:Scopus 1983-2021

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