Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14763
ชื่อเรื่อง: Development of a modified 100-gram oral glucose tolerance test for diagnosis of gestational diabetes mellitus and its diagnostic accuracy
ผู้แต่ง: Ruangvutilert P.
Chaemsaithong P.
Ruangrongmorakot K.
Kanokpongsakdi S.
Sunsaneevithayakul P.
Keywords: article
diagnostic accuracy
diagnostic value
female
glucose blood level
human
major clinical study
oral glucose tolerance test
pregnancy diabetes mellitus
sensitivity and specificity
analysis
blood
Diabetes, Gestational
diagnostic error
evaluation study
gestational age
glucose tolerance test
pregnancy
procedures
receiver operating characteristic
reproducibility
retrospective study
risk
glucose blood level
Blood Glucose
Diabetes, Gestational
Diagnostic Errors
Female
Gestational Age
Glucose Tolerance Test
Humans
Pregnancy
Reproducibility of Results
Retrospective Studies
Risk
ROC Curve
วันที่เผยแพร่: 2010
บทคัดย่อ: Objective: To develop a modified 100-g oral glucose tolerance test (100-g OGTT) for the diagnosis of gestational diabetes mellitus (GDM) in order to reduce the number of values needed for the test. Materials and Methods: Patient charts of pregnant women who completed the 100-g OGTT test at the antenatal clinic, Siriraj Hospital between 2005 and 2006 were reviewed. Cases diagnosed with GDM using standard 100-g OGTT were selected. In non-GDM cases, the last 100-g OGTT test was selected. Diagnostic performances of each glucose value and two or three values in various combinations were determined. Results: One thousand seven hundred sixty three women completed GDM diagnosis throughout their pregnancy. Four hundred three women had GDM while 1,360 subjects were non-GDM. Considering single glucose values, the highest level of accuracy, and the best ROC curve were obtained from the value at 2 hours after glucose ingestion (2-h glucose value) with 93.00% accuracy and the area under the ROC curve of 0.961. The combination of 2-h glucose value with fasting plasma glucose (FPG) showed 93.25% accuracy. FPG combined with 1-h and 2-h glucose values achieved 100% sensitivity with 92% accuracy. Conclusion: FPG in combined with 1-h and 2-h glucose values is an interesting alternative for the diagnosis of GDM.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14763
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77958112410&partnerID=40&md5=5aa5f4f8ae90ab04a1c26affe042a76d
ISSN: 1252208
Appears in Collections:Scopus 1983-2021

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