Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14678
ชื่อเรื่อง: A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives
ผู้แต่ง: Gornall K.C.
Samosorn S.
Tanwirat B.
Suksamrarn A.
Bremner J.B.
Kelso M.J.
Beck J.L.
Keywords: 2 naphthalenyl
5 nitro 2 phenylindolyl
berberine derivative
daunorubicin
double stranded DNA
guanine quadruplex
unclassified drug
article
DNA binding
DNA sequence
DNA structure
electrospray mass spectrometry
ligand binding
molecule
วันที่เผยแพร่: 2010
บทคัดย่อ: ESI mass spectrometry was used to assess the binding of 13-substituted, 5-nitro-2-phenylindolyl- and 2-naphthalenyl-based berberine derivatives to inter- and intramolecular G-quadruplex DNA molecules. In contrast with the parent berberine, the compounds showed selectivity for quadruplex over duplex DNA and stabilised the quadruplex structure. They represent a new class of quadruplex DNA-selective ligands. © 2010 The Royal Society of Chemistry.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14678
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956046998&doi=10.1039%2fc0cc01933j&partnerID=40&md5=d896c3fd3d71430da27ee1792567e721
ISSN: 13597345
Appears in Collections:Scopus 1983-2021

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