Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/13285
Title: Optimization of xylitol production by Candida tropicalis a26
Authors: Lorliam W.
Akaracharanya A.
Krajangsang S.
Tolieng V.
Tanasupawat S.
Issue Date: 2017
Abstract: Factors affecting xylitol production by Candida tropicalis A26 was investigated using Plackett-Burman design. According to 5 variables; media ingredients (3 variables), inoculums and pH; xylose and peptone were critical parameters affected on the xylitol production. Central composite design (CCD) was applied to screen for an optimal concentration of xylose and peptone. The highest xylitol production in flask scale was 42.52 g/l when xylose and peptone were 80 g/l and 4 g/l, respectively. The statistical regression model predicted the maximum xylitol production with 43.27 g/l, while the observed one was 42.52 g/l. Moreover, the production was scale up to 5 L by using stirred fermenter under the optimized condition. The highest xylitol production and xylitol yield after 42 h cultivation were 71.59 g/l and 0.89 g/g xylose, respectively. The results of statistical model and 5 L fermenter indicated that the optimized medium increased xylitol yield up to 1.45 folds compared with an un-optimized condition. Experimental design was successful by applied for improvement of xylitol production by C. tropicalis A26. © 2017, Chiang Mai University. All rights reserved.
URI: https://ir.swu.ac.th/jspui/handle/123456789/13285
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010748367&partnerID=40&md5=1818365ec900ba040ff63e13b1eceef5
ISSN: 1252526
Appears in Collections:Scopus 1983-2021

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