Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/13127
ชื่อเรื่อง: Herbal and dietary supplements related to diarrhea and acute kidney injury: A case report
ผู้แต่ง: Wanitsriphinyo S.
Tangkiatkumjai M.
Keywords: creatinine
enalapril
plant medicinal product
acute kidney failure
adult
Article
case report
causal attribution
clinical feature
creatinine blood level
dehydration
diabetes mellitus
diarrhea
dietary supplement
disease duration
fluid therapy
fruit
herb
herbal medicine
human
hyperkalemia
male
middle aged
Thai (people)
Acute Kidney Injury
adverse effects
diabetes mellitus
Diabetic Nephropathies
diarrhea
dietary supplement
phytotherapy
Acute Kidney Injury
Diabetes Mellitus
Diabetic Nephropathies
Diarrhea
Dietary Supplements
Enalapril
Fruit
Humans
Male
Middle Aged
Phytotherapy
Plant Preparations
วันที่เผยแพร่: 2017
บทคัดย่อ: There is very little evidence relating to the association of herbal medicine with diarrhea and the development of acute kidney injury (AKI). This study reports a case of diarrhea-induced AKI, possibly related to an individual ingesting copious amounts of homemade mixed fruit and herb puree. A 45-year-old Thai man with diabetes had diarrhea for 2 days, as a result of taking high amounts of a puree made up of eight mixed fruits and herbs over a 3-day period. He developed dehydration and stage 2 AKI, with a doubling of his serum creatinine. He had been receiving enalapril, as a prescribed medication, over one year. After he stopped taking both the puree and enalapril, and received fluid replacement therapy, within a week his serum creatinine had gradually decreased. The combination of puree, enalapril and AKI may also have induced hyperkalemia in this patient. Furthermore, the patient developed hyperphosphatemia due to his worsening kidney function, exacerbated by regularly taking some dietary supplements containing high levels of phosphate. His serum levels of potassium and phosphate returned to normal within a week, once the patient stopped both the puree and all dietary supplements, and had begun receiving treatment for hyperkalemia. The mixed fruit and herb puree taken by this man may have led to his diarrhea due to its effect; particularly if the patient was taking a high concentration of such a drink. Both the puree and enalapril are likely to attenuate the progression of kidney function. The causal relationship between the puree and AKI was probable (5 scores) assessed by the modified Naranjo algorithm. This is the first case report, as far as the authors are aware, relating the drinking of a mixed fruit and herbal puree to diarrhea and AKI in a patient with diabetes. This case can alert health care providers to the possibility that herbal medicine could induce diarrhea and develop acute kidney injury. © 2017 Walter de Gruyter GmbH, Berlin/Boston.
URI: https://ir.swu.ac.th/jspui/handle/123456789/13127
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015206551&doi=10.1515%2fjcim-2016-0061&partnerID=40&md5=02e32d35aa025c4ee184a7f242bdcdeb
ISSN: 15533840
Appears in Collections:Scopus 1983-2021

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