Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12739
Title: Prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status
Authors: Ariyawatkul K.
Lersbuasin P.
Keywords: 25 hydroxyvitamin D
albumin
alkaline phosphatase
calcium
magnesium
parathyroid hormone
phosphate
alkaline phosphatase
calcium
magnesium
parathyroid hormone
phosphate
serum albumin
vitamin D
albumin blood level
alkaline phosphatase blood level
Article
calcium blood level
controlled study
female
human
magnesium blood level
major clinical study
maternal blood
maternal serum
newborn
parathyroid hormone blood level
phosphate blood level
priority journal
umbilical cord blood
venous blood
vitamin blood level
vitamin D deficiency
adolescent
adult
blood
fetus blood
male
metabolism
middle aged
mother
pregnancy
prevalence
Thailand
vitamin D deficiency
young adult
Adolescent
Adult
Alkaline Phosphatase
Calcium
Female
Fetal Blood
Humans
Infant, Newborn
Magnesium
Male
Middle Aged
Mothers
Parathyroid Hormone
Phosphates
Pregnancy
Prevalence
Serum Albumin
Thailand
Vitamin D
Vitamin D Deficiency
Young Adult
Issue Date: 2018
Abstract: Vitamin D deficiency is common in Southeast Asia but there are limited data in pregnant women and neonates. This study aimed to determine the prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status. A total of 94 pregnant women and their neonates were included. Clinical data and venous maternal blood for calcium, phosphate, albumin, alkaline phosphatase, magnesium, intact parathyroid hormone (iPTH), and vitamin D (25OHD) were obtained on the day of labor. Cord blood was collected following delivery to evaluate vitamin D status of newborns. Mean serum maternal and cord blood 25OHD levels were 25.42 ± 8.07 and 14.85 ± 5.13 ng/mL. The prevalence of vitamin D deficiency (25OHD < 12 ng/mL) and insufficiency (25OHD 12–20 ng/mL) in cord blood of newborns were 20.2 and 69.1%, respectively. There was a significant correlation between maternal and cord blood vitamin D levels (r = 0.86; P < 0.001). The factors associated with cord blood vitamin D deficiency were low maternal 25OHD level and no vitamin D supplement during pregnancy. Conclusion: There is a high prevalence of vitamin D deficiency among Thai neonates. Adequate prenatal vitamin D supplementation should be implemented as routine antenatal care.What is Known:• Vitamin D deficiency is prevalent in Southeast Asia.• There are widespread vitamin D deficiency among Thai populations including pregnant women.What is New:• There is a high prevalence of vitamin D deficiency among Thai neonates.• The factors associated with cord blood vitamin D deficiency are low maternal vitamin D level and no vitamin D supplement during pregnancy. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.
URI: https://ir.swu.ac.th/jspui/handle/123456789/12739
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050270740&doi=10.1007%2fs00431-018-3210-2&partnerID=40&md5=54ae79b05713797c0f912808e33264e2
ISSN: 3406199
Appears in Collections:Scopus 1983-2021

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