Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12426
ชื่อเรื่อง: Four-dimensional computed tomography pattern enhancement of parathyroid lesions in preoperative localization of hyperparathyroidism
ผู้แต่ง: Songsaeng D.
Sricharoen T.
Khiewvan B.
Pusuwan P.
Chuthapisith S.
Sriussadaporn S.
Kunavisarut T.
Pongsapich W.
Chamsri N.
Boonma C.
Suwanbundit A.
Keywords: adult
aged
Article
cancer localization
clinical article
contrast enhancement
diagnostic accuracy
female
four dimensional computed tomography
frequency modulation
human
human tissue
hyperparathyroidism
hyperplasia
image analysis
lymph node
male
neuroradiology
parathyroid adenoma
parathyroid hyperplasia
parathyroid scintiscanning
parathyroidectomy
radiation attenuation
radiation dose
radiation exposure
retrospective study
sensitivity and specificity
thyroid gland
thyroid nodule
very elderly
x-ray computed tomography
วันที่เผยแพร่: 2019
บทคัดย่อ: Background: Four-dimensional computed tomography (4D-CT) improves the precision of pre-operative localization of hyperfunctioning parathyroid glands (HPGs). Objective: To analyze the role of pattern enhancement in 4D-CT imaging in hyperparathyroidism for differentiating HPGs from surrounding tissues for precision pre-operative localization of HPGs. Materials and Methods: The present retrospective study was conducted in patients who underwent 4D-CT scan of the parathyroid at the Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand between January 2013 and October 2016. Lesions were plotted for pattern enhancement, and mean Hounsfield units (HUs) of HPGs, lymph nodes, thyroid nodules, and thyroid glands were measured and analyzed. Results: Twenty-seven patients with 119 lesions were included. Significant difference was observed between both parathyroid adenoma and hyperplasia and thyroid gland during non-contrast phase and delayed 90-second phase. Attenuation value of less than 60 HUs in pre-contrast phase could differentiate HPGs from thyroid gland with 60% sensitivity and 85% specificity. Sensitivity of 4D-CT was 100% (95% Cl 73.5 to 100) for localization of all HPGs. Conclusion: Integration of clinical history data, conventional imaging, and 4D-CT imaging could improve differentiation of HPGs from surrounding tissues, thereby improving the precision of HPG localization during minimally invasive parathyroidectomy. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND | 2019.
URI: https://ir.swu.ac.th/jspui/handle/123456789/12426
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068785565&partnerID=40&md5=6a28a56fe2edcef00b420ccd420b149c
ISSN: 1252208
Appears in Collections:Scopus 1983-2021

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