Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12411
Full metadata record
DC FieldValueLanguage
dc.contributor.authorNantaphol S.
dc.contributor.authorKava A.A.
dc.contributor.authorChannon R.B.
dc.contributor.authorKondo T.
dc.contributor.authorSiangproh W.
dc.contributor.authorChailapakul O.
dc.contributor.authorHenry C.S.
dc.date.accessioned2021-04-05T03:03:14Z-
dc.date.available2021-04-05T03:03:14Z-
dc.date.issued2019
dc.identifier.issn32670
dc.identifier.other2-s2.0-85061010158
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85061010158&doi=10.1016%2fj.aca.2019.01.026&partnerID=40&md5=4c95dbcb4d574633c9ad064ea44d2b09
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/12411-
dc.description.abstractThe simultaneous detection of multiple analytes from a single sample is a critical tool for the analysis of real world samples. However, this is challenging to accomplish in the field by current electroanalytical techniques, where tuning assay conditions towards a target analyte often results in poor selectivity and sensitivity for other species in the mixture. In this work, an electrochemical paper-based analytical device (ePAD) capable of performing simultaneous electrochemical experiments in different solution conditions on a single sample was developed for the first time. We refer to the system as a Janus-ePAD after the two-faced Greek god because of the ability of the device to perform electrochemistry on the same sample under differing solution conditions at the same time with a single potentiostat. In a Janus-ePAD, a sample wicks down two channels from a single inlet towards two discreet reagent zones that adjust solution conditions, such as pH, before flow termination in two electrochemical detection zones. These zones feature independent working electrodes and shared reference and counter electrodes, facilitating simultaneous detection of multiple species at each species’ optimal solution condition. The device utility and applicability are demonstrated through the simultaneous detection of two biologically relevant species (norepinephrine and serotonin) and a common enzymatic assay product (p-aminophenol) at two different solution pH conditions. Janus-ePADs show great promise as an inexpensive and broadly applicable platform which can reduce the complexity and/or number of steps required in multiplexed analysis, while also operating under the optimized conditions of each species present in a mixture. © 2019 Elsevier B.V.
dc.subjectAnalytic equipment
dc.subjectChemical detection
dc.subjectElectrodes
dc.subjectMixtures
dc.subjectPaper
dc.subjectVoltage regulators
dc.subjectElectroanalytical techniques
dc.subjectELectrochemical detection
dc.subjectElectrochemical experiments
dc.subjectJanus
dc.subjectMultiple working conditions
dc.subjectPaper-based analytical devices
dc.subjectSelectivity and sensitivity
dc.subjectSimultaneous detection
dc.subjectElectrochemistry
dc.subject4 aminophenol
dc.subjectnoradrenalin
dc.subjectserotonin
dc.subjectanalytic method
dc.subjectArticle
dc.subjectcontrolled study
dc.subjectelectrochemical detection
dc.subjectelectrochemistry
dc.subjectenvironmental monitoring
dc.subjectenzymatic assay
dc.subjectenzyme linked immunosorbent assay
dc.subjecthydrophobicity
dc.subjectJanus electrochemistry
dc.subjectmicrofluidic paper based analytical device
dc.subjectpH
dc.subjectpriority journal
dc.subjectsensitivity analysis
dc.titleJanus electrochemistry: Simultaneous electrochemical detection at multiple working conditions in a paper-based analytical device
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationAnalytica Chimica Acta. Vol 1056, (2019), p.88-95
dc.identifier.doi10.1016/j.aca.2019.01.026
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.