Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12338
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dc.contributor.authorAngkananard T.
dc.contributor.authorJanma J.
dc.contributor.authorWannasiri T.
dc.contributor.authorSangthong P.
dc.contributor.authorChangsirikulchai S.
dc.date.accessioned2021-04-05T03:02:50Z-
dc.date.available2021-04-05T03:02:50Z-
dc.date.issued2019
dc.identifier.issn14712369
dc.identifier.other2-s2.0-85069000131
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85069000131&doi=10.1186%2fs12882-019-1418-7&partnerID=40&md5=2ecda8de679d154b2f3a220f3c15e49a
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/12338-
dc.description.abstractBackground: Factors associated with left ventricular systolic dysfunction (LVSD) of peritoneal dialysis (PD) patients are limited. We aim to explore and quantify the associated factors of LVSD among PD patients. Methods: Participants from a PD clinic treated between 2012 and 2014 at the HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, Nakhon Nayok, Thailand were recruited and divided into 2 groups according to their left ventricular ejection fraction (LVEF) (< 50% vs. ≥ 50%) with LVEF < 50% considered as LVSD. Correlations among the clinical, laboratory and echocardiographic variables were analyzed. The factors associated with LVSD were explored with univariate and multivariate logistic regression analyses. Beta coefficient along with odds ratio and 95% confidence interval (CI) were calculated and the P value < 0.05 was considered significant. Results: Among 103 subjects stratified as LVSD (n = 18, 17.5%). The mean (SD) age was 59.3 (12.7) years, and nearly halves were males. Preexisting CAD, diabetes (DM) and current smoking were 20 (19.4%), 63 (61.2%) and 23 (22.3%) patients, respectively. The median time of dialysis vintage was 12 (3, 24) months. Factors associated with LVSD and corresponding ORs with 95% CI by multivariate analysis were prior coronary artery disease (CAD) [5.08 (1.16, 22.19)], DM [6.36 (1.29, 31.49)], smoking [10.62 (2.17, 51.99)], neutrophil to lymphocyte ratio (NLR) > 3.6 [6.77 (1.41, 32.52)], and high serum phosphate [9.39 (2.16, 40.92)] were significantly associated with LVSD. Conclusions: Prior history of CAD, DM, smoking, high NLR and serum phosphate levels were found to be associated with LVSD for our PD patients. The evidence from prospective study is needed to confirm the predictive value of these variables. © 2019 The Author(s).
dc.subjectphosphate
dc.subjectadult
dc.subjectArticle
dc.subjectcoronary artery disease
dc.subjectcorrelational study
dc.subjectcross-sectional study
dc.subjectdiabetes mellitus
dc.subjectdisease association
dc.subjectechocardiography
dc.subjectfemale
dc.subjectheart left ventricle ejection fraction
dc.subjecthuman
dc.subjecthuman cell
dc.subjectlaboratory test
dc.subjectleft ventricular systolic dysfunction
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical history
dc.subjectmiddle aged
dc.subjectneutrophil lymphocyte ratio
dc.subjectperitoneal dialysis
dc.subjectphosphate blood level
dc.subjectsex ratio
dc.subjectsmoking
dc.subjectThai (people)
dc.subjectuniversity hospital
dc.subjectaged
dc.subjectchronic kidney failure
dc.subjectcomplication
dc.subjectepidemiology
dc.subjectheart left ventricle function
dc.subjectrisk factor
dc.subjectsystole
dc.subjectThailand
dc.subjectAged
dc.subjectCross-Sectional Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectKidney Failure, Chronic
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPeritoneal Dialysis
dc.subjectRisk Factors
dc.subjectSystole
dc.subjectThailand
dc.subjectVentricular Dysfunction, Left
dc.titleAssociations of left ventricular systolic dysfunction with the factors among Thai patients on peritoneal dialysis: A cross-sectional study
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationBMC Nephrology. Vol 20, No.1 (2019)
dc.identifier.doi10.1186/s12882-019-1418-7
Appears in Collections:Scopus 1983-2021

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