Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12045
ชื่อเรื่อง: Probiotic characterization and in vitro cholesterol lowering effects of lactic acid bacteria isolated from healthy thai infants
ผู้แต่ง: Sirichotinun N.
Pachekrepapol U.
Nantavisai K.
Taweechotipatr M.
Nilwarangkoon S.
วันที่เผยแพร่: 2020
บทคัดย่อ: Hypercholesterolemia is one of the major health problems affecting people worldwide. Some probiotic lactic acid bacteria possess cholesterol lowering ability. One-hundred lactic acid bacteria isolated from the feces of healthy Thai infants were screened for bile salt hydrolase activity and cholesterol assimilation ability. Seven isolates expressed strong bile salt hydrolase activity and 7 isolates exhibited cholesterol assimilation properties. In total, 11 probiotic candidates were characterized for their general probiotic properties including acid and bile tolerance, adherence to Caco-2 cells and genotypic identification using 16S rRNA gene sequencing. Eight isolates were identified as Enterococcus faecalis and others were E. faecium, E. durans, and Lactococcus garvieae. All selected isolates survived after incubation at pH 3 and 4, and in 0.3% and 0.8% bile. The strain E. faecium MSMC 25-2 exhibited the highest level of adhesion to Caco-2 cells at 8.8% compared to L. rhamnosus GG. © 2020, Prince of Songkla University. All rights reserved.
URI: https://ir.swu.ac.th/jspui/handle/123456789/12045
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085085942&partnerID=40&md5=a5a8fc7c2e544fb6b46f33da57717d5e
ISSN: 1253395
Appears in Collections:Scopus 1983-2021

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