Publication:
The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects

2
0

Issued Date

2005

Resource Type

Article

File Type

application/pdf

ISSN

1354523X

DOI

10.1111/j.1601-0825.2005.01119.x

Other identifier(s)

2-s2.0-25144510575

Rights Holder(s)

Scopus

Bibliographic Citation

Oral Diseases. Vol 11, No.5 (2005), p.293-298

Suggested Citation

Promsudthi A., Pimapansri S., Deerochanawong C., Kanchanavasita W. The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects. Oral Diseases. Vol 11, No.5 (2005), p.293-298. doi:10.1111/j.1601-0825.2005.01119.x Retrieved from: https://hdl.handle.net/20.500.14740/6083

Title

The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects

Author(s)

Promsudthi A.
 Pimapansri S.
 Deerochanawong C.
 Kanchanavasita W.

Abstract

OBJECTIVE: The purpose of this study was to examine the effect of periodontal therapy on glycemic control in older type 2 diabetic patients. METHODS: Fifty-two diabetic patients, age 55-80 years (mean age = 61 years), with glycated hemoglobin (HbAIc) 7.5-11.0% (mean ± s.d. = 8.98 ± 0.88) and severe periodontitis were included in the present study. The treatment group received mechanical periodontal treatment combined with systemic doxycycline, 1OO mg day-1 for 14 days. The control group received neither periodontal treatment nor systemic doxycycline. Clinical periodontal parameters, fasting plasma glucose (FPG), and HbAIc levels were measures at baseline and 3 months. RESULTS: Periodontal treatment significantly improved periodontal status of the treatment group (P < 0.05), however the reduction in the level of FPG and HbAIc did not reach significance. In the control group, no significant changes in clinical periodontal parameters, FPG and HbAIc levels were observed, except for significant increase in attachment loss (P < 0.05). Comparing the two groups, although the 3-month level of HbAIc of the treatment group was lower than that of the control group, the difference did not reach significance. CONCLUSIONS: The results of the present study indicate that the periodontal condition of older Thais with uncontrolled diabetes is: (a) significantly improved 3 months after mechanical periodontal therapy with adjunctive systemic antimicrobial treatment, and (b) rapidly deteriorating without periodontal treatment. The effect of periodontal therapy on the glycemic control of older uncontrolled diabetics will require further studies that will have to include much larger sample sizes. © 2005 Blackwell Munksgaard All rights reserved.

Subject(s)

Doxycycline
 Glycosylated hemoglobin
 Hemoglobin A1c
 Antiinfective agent
 Glycosylated hemoglobin
 Adult
 Aged
 Article
 Controlled study
 Dental care
 Dental health
 Female
 Gingiva bleeding
 Glucose blood level
 Human
 Major clinical study
 Male
 Mouth hygiene
 Non insulin dependent diabetes mellitus
 Priority journal
 Tooth disease
 Tooth plaque
 Blood
 Clinical trial
 Controlled clinical trial
 Glucose blood level
 Metabolism
 Middle aged
 Non insulin dependent diabetes mellitus
 Periodontics
 Periodontitis
 Preventive dentistry
 Tooth plaque
 Aged
 Aged, 80 and over
 Anti-Bacterial Agents
 Blood Glucose
 Dental Plaque Index
 Dental Scaling
 Diabetes Mellitus, Type 2
 Doxycycline
 Female
 Hemoglobin A, Glycosylated
 Humans
 Male
 Middle Aged
 Periodontal Index
 Periodontitis

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URI

https://hdl.handle.net/20.500.14740/6083

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Scopus: Year 1983-2021

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