Publication: Femoral fracture type can be predicted from femoral structure: A finite element study validated by digital volume correlation experiments
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Issued Date
2018
Resource Type
File Type
application/pdf
ISSN
7360266
Other identifier(s)
2-s2.0-85044958576
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of Orthopaedic Research. Vol 36, No.3 (2018), p.993-1001
Suggested Citation
Ridzwan M.I.Z., Sukjamsri C., Pal B., Van Arkel R.J., Bell A., Khanna M., Baskaradas A., Abel R., Boughton O., Cobb J., Hansen U.N. Femoral fracture type can be predicted from femoral structure: A finite element study validated by digital volume correlation experiments. Journal of Orthopaedic Research. Vol 36, No.3 (2018), p.993-1001. doi:10.1002/jor.23669 Retrieved from: https://hdl.handle.net/20.500.14740/3695
Abstract
Proximal femoral fractures can be categorized into two main types: Neck and intertrochanteric fractures accounting for 53% and 43% of all proximal femoral fractures, respectively. The possibility to predict the type of fracture a specific patient is predisposed to would allow drug and exercise therapies, hip protector design, and prophylactic surgery to be better targeted for this patient rendering fracture preventing strategies more effective. This study hypothesized that the type of fracture is closely related to the patient-specific femoral structure and predictable by finite element (FE) methods. Fourteen femora were DXA scanned, CT scanned, and mechanically tested to fracture. FE-predicted fracture patterns were compared to experimentally observed fracture patterns. Measurements of strain patterns to explain neck and intertrochanteric fracture patterns were performed using a digital volume correlation (DVC) technique and compared to FE-predicted strains and experimentally observed fracture patterns. Although loaded identically, the femora exhibited different fracture types (six neck and eight intertrochanteric fractures). CT-based FE models matched the experimental observations well (86%) demonstrating that the fracture type can be predicted. DVC-measured and FE-predicted strains showed obvious consistency. Neither DXA-based BMD nor any morphologic characteristics such as neck diameter, femoral neck length, or neck shaft angle were associated with fracture type. In conclusion, patient-specific femoral structure correlates with fracture type and FE analyses were able to predict these fracture types. Also, the demonstration of FE and DVC as metrics of the strains in bones may be of substantial clinical value, informing treatment strategies and device selection and design. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:993–1001, 2018. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.
Subject(s)
Adult
Aged
Analysis
Article
Bone structure
Cervical spine fracture
Digital volume correlation analysis
Dual energy X ray absorptiometry
Female
Femoral neck
Femur fracture
Femur intertrochanteric fracture
Human
Male
Mechanical stimulus test
Priority journal
Treatment planning
X-ray computed tomography
Bone density
Diagnostic imaging
Femoral neck fracture
Femur
Finite element analysis
Middle aged
Validation study
Very elderly
Adult
Aged
Aged, 80 and over
Bone Density
Female
Femoral Neck Fractures
Femur
Finite Element Analysis
Humans
Male
Middle Aged
Aged
Analysis
Article
Bone structure
Cervical spine fracture
Digital volume correlation analysis
Dual energy X ray absorptiometry
Female
Femoral neck
Femur fracture
Femur intertrochanteric fracture
Human
Male
Mechanical stimulus test
Priority journal
Treatment planning
X-ray computed tomography
Bone density
Diagnostic imaging
Femoral neck fracture
Femur
Finite element analysis
Middle aged
Validation study
Very elderly
Adult
Aged
Aged, 80 and over
Bone Density
Female
Femoral Neck Fractures
Femur
Finite Element Analysis
Humans
Male
Middle Aged