Publication:
Design of polymeric nanoparticles for the encapsulation of monoacylglycerol

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Issued Date

2010

Resource Type

Article

File Type

application/pdf

ISSN

0303402X

DOI

10.1007/s00396-010-2216-8

Other identifier(s)

2-s2.0-77956461155

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Colloid and Polymer Science. Vol 288, No.9 (2010), p.959-967

Suggested Citation

Chiewpattanakul P., Covis R., Vanderesse R., Thanomsub B., Marie E., Durand A. Design of polymeric nanoparticles for the encapsulation of monoacylglycerol. Colloid and Polymer Science. Vol 288, No.9 (2010), p.959-967. doi:10.1007/s00396-010-2216-8 Retrieved from: https://hdl.handle.net/20.500.14740/7570

Title

Design of polymeric nanoparticles for the encapsulation of monoacylglycerol

Author(s)

Chiewpattanakul P.
 Covis R.
 Vanderesse R.
 Thanomsub B.
 Marie E.
 Durand A.

Abstract

Dextran-covered nanoparticles were produced by two different processes: emulsion/solvent evaporation and nanoprecipitation for the encapsulation of monomyristin. The inner core was formed by poly(lactic acid) or by a hydrophobically modified dextran (carrying n-decyl chains). According to the core materials and/or to the process, the average size of nanoparticles as well as the extent of aggregate formation was modulated. It was shown that the presence of monomyristin induced significant modifications on the characteristics of the resulting suspension (size and aggregate formation). Varying the matrix polymer as well as the amount of monomyristin in the feed allowed obtaining nanoparticles with convenient size. The use of hydrophobically modified dextran as the matrix material appeared promising. © Springer-Verlag 2010.

Subject(s)

Aggregate formation
 Average size
 Core material
 Different process
 Emulsion solvent evaporation
 Hydrophobically modified dextran
 Inner core
 Matrix materials
 Matrix polymers
 Monomyristin
 Nanoprecipitation
 Poly(lactic acid)
 Polymeric nanoparticles
 Body fluids
 Coremaking
 Dextran
 Emulsification
 Evaporation
 Glucose
 Glycerol
 Lactic acid
 Organic acids
 Polymers
 Nanoparticles
 Dextran
 Monoacylglycerol
 Monomyristin
 Nanoparticle
 Polylactic acid
 Unclassified drug
 Article
 Chemical modification
 Chemical structure
 Evaporation
 Hydrophobicity
 Nanoemulsion
 Nanoencapsulation
 Particle size
 Precipitation
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URI

https://hdl.handle.net/20.500.14740/7570

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Scopus: Year 1983-2021

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