Publication:
Neutrophil to lymphocyte ratio as a marker in patients with non-arteritic anterior ischemic optic neuropathy in hrh princess maha chakri sirindhorn medical center

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Issued Date

2021

Resource Type

Article

Language

eng

File Type

application/pdf

ISSN

1252208

DOI

10.35755/jmedassocthai.2021.S03.00019

Other identifier(s)

2-s2.0-85116066280

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S44-S50

Suggested Citation

Sinsawad P., Boonhaijaroen T. Neutrophil to lymphocyte ratio as a marker in patients with non-arteritic anterior ischemic optic neuropathy in hrh princess maha chakri sirindhorn medical center. Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S44-S50. doi:10.35755/jmedassocthai.2021.S03.00019 Retrieved from: https://hdl.handle.net/20.500.14740/3773

Title

Neutrophil to lymphocyte ratio as a marker in patients with non-arteritic anterior ischemic optic neuropathy in hrh princess maha chakri sirindhorn medical center

Author(s)

Sinsawad P.
 Boonhaijaroen T.

Abstract

Background: Non anterior ischemic optic neuropathy (NAION) is the most common form of ischemic optic neuropathy. usually associated with systemic vasculopathy disease and has variable visual outcomes. The mechanism of NAION is not fully understood and there is no treatment have been proven to be standard treatment. Objective: To evaluate Neutrophil to Lymphocyte Ratio in Non-arteritic Anterior Ischemic Optic Neuropathy patients in HRH Princess Maha Chakri Sirindhorn Medical Center. Design: Retrospective crossectional study. Materials and Methods: 90 patients in the present study were categorized equally into three groups. Group one was those who were diagnosed with NAION. Group two and three as control groups were those who were diagnosed with cataract with and without systemic diseases respectively. The complete blood count was examined at the first visit of NAION or at the pre-operative day. NLR in each group was calculated and compared. Results: The average of NLR in the group one was 2.25, in the group two and group three were 1.69 and 1.74 respectively. The comparison of mean continuous variable between 3 groups using Oneway ANOVA was analysed. NLR in group one was higher with statistical significance (p<0.05) when compared with group two but there was no statistical significance between group one and group three or group two and group three. The level of NLR has the negative correlation with the improvement of BCVA at 3 months. Conclusion: NLR ratio is one of the marker that can be found elevated when there is an inflammatory reaction, in the present study there is a significant higher of NLR ratio in NAION group and has negative correlation with vision at three months, NLR could be used as a prognostic indicator for the prediction of Visual outcome. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND, 2021.

Subject(s)

C reactive protein
 Adult
 Afferent pupillary defect
 Anterior ischemic optic neuropathy
 Article
 Best corrected visual acuity
 Blood cell count
 Cataract
 Color vision test
 Controlled study
 Cross-sectional study
 Diabetes mellitus
 Diagnostic test accuracy study
 Dyslipidemia
 Erythrocyte sedimentation rate
 Female
 Human
 Hypertension
 Inflammation
 Major clinical study
 Male
 Neutrophil lymphocyte ratio
 Ophthalmoscopy
 Outcome assessment
 Receiver operating characteristic
 Retrospective study
 Senile cataract
 Sensitivity and specificity
 Teaching hospital
 Thailand
 Urea nitrogen blood level
 Venereal disease reaction test
 Visual field
 Visual field defect
 Visual impairment

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URI

https://hdl.handle.net/20.500.14740/3773

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Scopus: Year 1983-2021

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