Publication:
Effect of nicotine polyestex gum on smoking cessation and quality of life

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Issued Date

2008

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-57149106979

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 91, No.11 (2008), p.1656-1662

Suggested Citation

Rungruanghiranya S., Ekpanyaskul C., Hattapornsawan Y., Tundulawessa Y. Effect of nicotine polyestex gum on smoking cessation and quality of life. Journal of the Medical Association of Thailand. Vol 91, No.11 (2008), p.1656-1662. Retrieved from: https://hdl.handle.net/20.500.14740/3860

Title

Effect of nicotine polyestex gum on smoking cessation and quality of life

Author(s)

Rungruanghiranya S.
 Ekpanyaskul C.
 Hattapornsawan Y.
 Tundulawessa Y.

Abstract

Objective: To determine the effectiveness and safety of the novel nicotine polyestex gum for smoking cessation, along with its impact on the quality of life (QOL). Material and Method: A double-blind, placebo-controlled, randomized clinical trial was conducted on 43 smokers. All of them received either nicotine gum or placebo. Only those who could quit completely and continuously by the end of 3 months were considered total abstinence. QOL was also measured using WHO questionnaires. Results: Treatment with nicotine polyestex gum resulted in significantly greater abstinence rate at 3 months compared with placebo (50% vs. 9%; p = 0.003). Adverse events were modest and not encountered more often than those seen in the placebo group. QOL at 3-months improved in both groups, but there was no statistically significant difference between the groups. Conclusion: Nicotine polyestex gum is effective and safe for smoking cessation. It is also associated with significant improvement in the QOL.

Subject(s)

Nicotine
 Nicotine gum
 Placebo
 Abstinence
 Adult
 Article
 Clinical article
 Clinical trial
 Controlled clinical trial
 Controlled study
 Dizziness
 Double blind procedure
 Drug efficacy
 Drug safety
 Dyspepsia
 Female
 Health care organization
 Human
 Jaw disease
 Male
 Mouth pain
 Quality of life
 Questionnaire
 Randomized controlled trial
 Scoring system
 Smoking cessation
 Tobacco dependence
 Adult
 Chewing Gum
 Double-Blind Method
 Health Status Indicators
 Health Surveys
 Humans
 Male
 Middle Aged
 Nicotine
 Prospective Studies
 Quality of Life
 Questionnaires
 Smoking
 Smoking Cessation
 Young Adult

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URI

https://hdl.handle.net/20.500.14740/3860

Collections

Scopus: Year 1983-2021

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