Publication:
An oral nutraceutical containing antioxidants, minerals and glycosaminoglycans improves skin roughness and fine wrinkles

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0

Issued Date

2009

Resource Type

Article

File Type

application/pdf

ISSN

1425463

DOI

10.1111/j.1468-2494.2009.00513.x

Other identifier(s)

2-s2.0-70350128005

Rights Holder(s)

Scopus

Bibliographic Citation

International Journal of Cosmetic Science. Vol 31, No.6 (2009), p.427-435

Suggested Citation

Udompataikul M., Sripiroj P., Palungwachira P. An oral nutraceutical containing antioxidants, minerals and glycosaminoglycans improves skin roughness and fine wrinkles. International Journal of Cosmetic Science. Vol 31, No.6 (2009), p.427-435. doi:10.1111/j.1468-2494.2009.00513.x Retrieved from: https://hdl.handle.net/20.500.14740/7686

Title

An oral nutraceutical containing antioxidants, minerals and glycosaminoglycans improves skin roughness and fine wrinkles

Author(s)

Udompataikul M.
 Sripiroj P.
 Palungwachira P.

Abstract

Synopsis Various nutraceuticals (dietary supplements) are claimed to have cutaneous antiageing properties, however, there are a limited number of research studies supporting these claims. The objective of this research was to study the effectiveness of an oral nutraceutical containing antioxidants, minerals and glycosaminoglycans on cutaneous ageing. In this double-blind, placebo-controlled trial, 60 women aged 35-60 years were randomized to receive oral dietary supplement (n = 30) or placebo (n = 30), once daily for 12 weeks. The depth of skin roughness and fine wrinkles were measured using surface evaluation of skin parameters for living skin (Visioscan) at baseline, and at the 4, 8 and 12 weeks of treatment. Surface evaluation using a replica film (Visiometer) at baseline and at the 12th week of treatment was also carried out. Statistical differences in objective skin improvement were assessed by the independent t-test. The volunteers' satisfaction was tested using the chi-squared test. The baseline depth of skin roughness and fine wrinkles in the treatment group and the placebo group were 100.5 and 100 μm, respectively. At the end of the study, the depth of skin roughness and fine wrinkles in the treatment group showed a 21.2% improvement, whereas improvement in the control group was 1.7%. This difference was statistically significant (P < 0.001). With regard to the volunteers' satisfaction, there was no statistically significant decrease in the homogenization of skin colour, however, a statistically significant reduction in pore size and depth of skin roughness and fine wrinkles were observed (P < 0.05). No side effects were noted throughout the study. The oral dietary supplement containing antioxidants, minerals and glycosaminoglycans improved skin roughness and fine wrinkles but did not affect skin colour change in female volunteers. © 2009 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

Subject(s)

Antioxidant
 Glycosaminoglycan
 Mineral
 Nutraceutical
 Placebo
 Radiance marine q10
 Unclassified drug
 Absence of side effects
 Adult
 Article
 Clinical trial
 Controlled clinical trial
 Controlled study
 Cutaneous parameters
 Diet supplementation
 Double blind procedure
 Drug efficacy
 Evaluation
 Female
 Human
 Major clinical study
 Patient satisfaction
 Randomized controlled trial
 Skin color
 Surface property
 Treatment response
 Wrinkle
 Administration, Oral
 Adult
 Antioxidants
 Consumer Satisfaction
 Dietary Supplements
 Double-Blind Method
 Female
 Glycosaminoglycans
 Humans
 Middle Aged
 Minerals
 Questionnaires
 Skin Aging
 Surface Properties
 Ubiquinone

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URI

https://hdl.handle.net/20.500.14740/7686

Collections

Scopus: Year 1983-2021

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