Publication:
Chlorhexidine allergy: Current challenges and future prospects

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Issued Date

2020

Resource Type

Review

File Type

application/pdf

ISSN

11786965

DOI

10.2147/JAA.S207980

Other identifier(s)

2-s2.0-85081897066

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of Asthma and Allergy. Vol 13, (2020), p.127-133

Suggested Citation

Chiewchalermsri C., Sompornrattanaphan M., Wongsa C., Thongngarm T. Chlorhexidine allergy: Current challenges and future prospects. Journal of Asthma and Allergy. Vol 13, (2020), p.127-133. doi:10.2147/JAA.S207980 Retrieved from: https://hdl.handle.net/20.500.14740/4975

Title

Chlorhexidine allergy: Current challenges and future prospects

Author(s)

Chiewchalermsri C.
 Sompornrattanaphan M.
 Wongsa C.
 Thongngarm T.

Abstract

Chlorhexidine is a synthetic bisbiguanide antiseptic and was introduced in healthcare use in 1954. Allergy to chlorhexidine has been increasingly reported particularly in the perioperative and medical procedural settings. The hypersensitivity reactions range from mild cutaneous reactions to anaphylaxis or death. There are many products and medical devices containing chlorhexidine that sometimes lack standardized labeling. With the various routes of chlorhexidine exposure, accidental or recurrent reactions in chlorhexidine-allergic patients have been reported. Therefore, we aim to review the most recent evidence in clinical manifestations, diagnostic methods, management, and preventive measures with a focus on the unique features of chlorhexidine allergy. © 2020 Chiewchalermsri et al.

Subject(s)

Antibiotic agent
 Antiinfective agent
 Chlorhexidine
 Disinfectant agent
 Immunoglobulin E
 Allergic reaction
 Allergy
 Anaphylaxis
 Angioneurotic edema
 Basophil activation test
 Contact allergy
 Diagnostic procedure
 Drug eruption
 Drug hypersensitivity
 Eczema
 Health care
 Human
 Hypersensitivity
 Intracutaneous test
 Patch test
 Prevalence
 Prick test
 Review
 Sensitivity and specificity
 Sensitization
 Skin allergy
 Skin manifestation

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URI

https://hdl.handle.net/20.500.14740/4975

Collections

Scopus: Year 1983-2021

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Review

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