Publication:
Epidemiology of candida infections in HRH princess maha chakri sirindhorn medical center, srinakharinwirot university

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Issued Date

2015

Resource Type

Article

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application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84957716993

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 98, (2015), p.S66-S70

Suggested Citation

Tantisiriwat W., Santiwattanakul S. Epidemiology of candida infections in HRH princess maha chakri sirindhorn medical center, srinakharinwirot university. Journal of the Medical Association of Thailand. Vol 98, (2015), p.S66-S70. Retrieved from: https://hdl.handle.net/20.500.14740/6050

Title

Epidemiology of candida infections in HRH princess maha chakri sirindhorn medical center, srinakharinwirot university

Author(s)

Tantisiriwat W.
 Santiwattanakul S.

Abstract

Objective: To identify the epidemiology of candida isolations in HRH Princess Maha Chakri Sirindhorn Medical Center and the sensitivity of all candida species to fluconazole. Material and Method: Two hundred of Candida albicans and other Candida species from clinical specimens were collected from microbiological department between January 2010 and April 2012. All Candida were identified by standard methods and the sensitivity of fluconazole was tested by using fluconazole E test test. Results: There were 8 species of Candida in this study including: C. albicans (n = 94), C. tropicalis (n = 66), C. glabrata (n = 11), C. guilliermondii (n = 10), C. parapsilosis (n = 9), C. zeylanoides (n = 4), C. keyfr (C. pseudotropicalis) (n = 2), C. lusitaniae (n = 1), Candida species (n = 3). The percentage of non-albicans Candida spp. was slightly higher than C. albicans (53% vs. 47%). C. tropicalis was identified as the highest percentage of all non-albicans Candida spp. Fluconazole resistant strains were detected among C. albicans (35.71%), C. tropicalis (13.85%), C. guilliermondii (20.0%), and C. zeylanoides (50.0%). The common spp. with highest percentage of resistant strain was C. albicans. Conclusion: Fluconazole could be used as the first-line antifungal for candidiasis at HRH Princess Maha Chakri Sirindhorn Medical Center. Empirical treatment with amphotericin B and stepping down to fluconazole when sensitivity suggested might be the recommendation for severe cases in our setting. © 2015, Medical Association of Thailand. All rights reserved.

Subject(s)

Amphotericin B
 Fluconazole
 Amphotericin B
 Antifungal agent
 Fluconazole
 Antibiotic sensitivity
 Article
 Candida albicans
 Candida glabrata
 Candida parapsilosis
 Candida tropicalis
 Candida zeylanoides
 Candidemia
 Candidiasis
 Clavispora lusitaniae
 Kluyveromyces marxianus
 Meyerozyma guilliermondii
 Minimum inhibitory concentration
 Nonhuman
 Prospective study
 Sensitivity analysis
 Candida
 Candidiasis
 Human
 Isolation and purification
 Microbial sensitivity test
 Procedures
 United States
 University hospital
 Academic Medical Centers
 Amphotericin B
 Antifungal Agents
 Candida
 Candida albicans
 Candidiasis
 Fluconazole
 Humans
 Microbial Sensitivity Tests
 Prospective Studies
 United States

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URI

https://hdl.handle.net/20.500.14740/6050

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Scopus: Year 1983-2021

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