Fabrication of P 2O 5-CaO-Na 2O glasses doped with zinc oxide for artificial bone applications

Abstract

The purpose of this work was to study the effect of ZnO on properties of P 2O 5-CaO-Na 2O glass system for bone substituting applications. The glass formula used in this study is 45P 2O 5 - (30-x)CaO - 25Na 2O - xZnO where x = 0, 1, 3, and 5 mol%. The corresponding glasses were prepared by conventional glass melting technique at 1000 °C for 1 h. Thermal parameters of each glass were studied by differential thermal analysis (DTA). These glasses were investigated in terms of infrared spectra and in vitro bioactivity. DTA results gave the glass transition temperatures in a range 227-280°C and crystallization temperatures in the range 521-529°C. Form FTIR results, the infrared spectra of all glass samples showed vibrations of phosphate network and the transmittance intensity of glass systems decreased with increasing ZnO content. All glass samples were exhibited the growth of apatite cells at the surface after immersed in SBF for 7 days. The optimum composition was found for the glass samples containing 5 mol% ZnO which contained the most apatite layer formation. © (2012) Trans Tech Publications.