Publication:
Any heart failure treatments associated with worsening renal function in patients admitted due to acute heart failure?

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Issued Date

2021

Resource Type

Article

File Type

application/pdf

ISSN

0886022X

DOI

10.1080/0886022X.2020.1858100

Other identifier(s)

2-s2.0-85099112324

Rights

Srinakharinwirot University

Rights Holder(s)

Scopus

Bibliographic Citation

Renal Failure. Vol 43, No.1 (2021), p.123-127

Suggested Citation

Limkunakul C., Srisantithum B., Lerdrattanasakulchai Y., Laksomya T., Jungpanich J., Sawanyawisuth K. Any heart failure treatments associated with worsening renal function in patients admitted due to acute heart failure?. Renal Failure. Vol 43, No.1 (2021), p.123-127. doi:10.1080/0886022X.2020.1858100 Retrieved from: https://hdl.handle.net/20.500.14740/4743

Title

Any heart failure treatments associated with worsening renal function in patients admitted due to acute heart failure?

Author(s)

Limkunakul C.
 Srisantithum B.
 Lerdrattanasakulchai Y.
 Laksomya T.
 Jungpanich J.
 Sawanyawisuth K.

Abstract

Background: Worsening renal function (WRF) occurs in approximately 25% of acute heart failure patients, and both baseline characteristics and heart failure treatment may increase the risk of WRF. This study aimed to evaluate additional risk factors for WRF in acute heart failure, particularly those related to heart failure treatment. Methods: This was a retrospective, observational, analytical study. The inclusion criteria were age 18 years or over, hospital admission due to acute heart failure, and having undergone at least two serum creatinine tests during admission. The eligible patients were classified into two groups: WRF and non-WRF. Predictors for WRF (including treatment parameters) were determined using logistic regression analysis. Results: During the study period, there were 301 eligible patients who met the study criteria. Of those, 82 (27.24%) had WRF. There were two independent factors associated with WRF occurrence: baseline diastolic blood pressure and beta blocker treatment, with adjusted odds ratios (95% confidence interval) of 1.060 (1.008, 1.114) and 0.064 (0.006, 0.634), respectively. The Hosmer-Lemeshow Chi square for the final model was 6.11 (p =.634).   Conclusions: After examining several heart failure treatments and baseline factors, we found that beta blocker treatment results improvement in kidney function. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Subject(s)

Angiotensin receptor antagonist
 Antibiotic agent
 Beta adrenergic receptor blocking agent
 Brain natriuretic peptide
 Calcium channel blocking agent
 Contrast medium
 Creatinine
 Dipeptidyl carboxypeptidase inhibitor
 Furosemide
 Glyceryl trinitrate
 Hemoglobin
 Inotropic agent
 Nonsteroid antiinflammatory agent
 Spironolactone
 Acute heart failure
 Aged
 Article
 Chronic kidney failure
 Controlled study
 Creatinine blood level
 Diastolic blood pressure
 Disease exacerbation
 Female
 Heart ejection fraction
 Heart rate
 Hospital admission
 Human
 Human tissue
 Kidney function
 Major clinical study
 Male
 Observational study
 Oxygen saturation
 Priority journal
 Retrospective study
 Risk factor
 Sodium blood level
 Systolic blood pressure

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URI

https://hdl.handle.net/20.500.14740/4743

Collections

Scopus: Year 1983-2021

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