Publication: Autophagy in epithelial homeostasis and defense
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0
Issued Date
2013
Resource Type
File Type
application/pdf
ISSN
19450494
Other identifier(s)
2-s2.0-84884299292
Rights Holder(s)
Scopus
Bibliographic Citation
Frontiers in Bioscience - Elite. Vol 5 E, No.3 (2013), p.1000-1010
Suggested Citation
Sukseree S., Eckhart L., Tschachler E., Watanapokasin R. Autophagy in epithelial homeostasis and defense. Frontiers in Bioscience - Elite. Vol 5 E, No.3 (2013), p.1000-1010. Retrieved from: https://hdl.handle.net/20.500.14740/6653
Author(s)
Abstract
Autophagy delivers protein aggregates, damaged organelles and intracellular microorganisms to the lysosome for degradation. The epidermis and other epithelia show significant levels of autophagy, however, the functions of autophagy in these tissues have remained elusive until recently. Here we review the experimental approaches for the investigation of autophagy in epithelia and discuss the roles of autophagy in epithelial cells with a focus on epidermal keratinocytes and thymic epithelial cells.
Subject(s)
Adaptor protein
Autophagy protein 5
Autophagy protein 7
Cytoplasm protein
Green fluorescent protein
Hybrid protein
NBR1 protein
Nucleotide binding oligomerization domain like receptor
Pattern recognition receptor
Protein p62
Retinoic acid inducible protein I
Unclassified drug
Article
Autophagosome
Autophagy
Cell differentiation
Cell function
Cell survival
Cytoplasm
Epidermis
Epithelium cell
Gene deletion
Innate immunity
Intestine epithelium
Keratinocyte
Knockout gene
Lung alveolus epithelium
Lysosome
Mouse
Nonhuman
Protein aggregation
Protein binding
Protein degradation
Protein processing
Protein ubiquitinylation
Skin appendage
Stratum corneum
Stress
Transgenic mouse
Ultraviolet A radiation
Ultraviolet B radiation
Virus immunity
Autophagy protein 5
Autophagy protein 7
Cytoplasm protein
Green fluorescent protein
Hybrid protein
NBR1 protein
Nucleotide binding oligomerization domain like receptor
Pattern recognition receptor
Protein p62
Retinoic acid inducible protein I
Unclassified drug
Article
Autophagosome
Autophagy
Cell differentiation
Cell function
Cell survival
Cytoplasm
Epidermis
Epithelium cell
Gene deletion
Innate immunity
Intestine epithelium
Keratinocyte
Knockout gene
Lung alveolus epithelium
Lysosome
Mouse
Nonhuman
Protein aggregation
Protein binding
Protein degradation
Protein processing
Protein ubiquitinylation
Skin appendage
Stratum corneum
Stress
Transgenic mouse
Ultraviolet A radiation
Ultraviolet B radiation
Virus immunity