Publication: Analysis of FTIR Spectra, Flavonoid Content and Anti-Tyrosinase Activity of Extracts and Lotion from Garcinia schomburgkiana by Multivariate Method
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Issued Date
2022
Resource Type
Language
eng
File Type
application/pdf
ISSN
27740226
Rights Holder(s)
มหาวิทยาลัยศรีนครินทรวิโรฒ
Bibliographic Citation
Journal of Language Teaching and Research. Vol 13, No.2 (2022), p.308-314
Suggested Citation
Thummajitsakul S., Silprasit K. Analysis of FTIR Spectra, Flavonoid Content and Anti-Tyrosinase Activity of Extracts and Lotion from Garcinia schomburgkiana by Multivariate Method. Journal of Language Teaching and Research. Vol 13, No.2 (2022), p.308-314. doi:10.48048/tis.2022.5780 Retrieved from: https://hdl.handle.net/20.500.14740/9818
Author(s)
Abstract
In this study, fourier transform infrared (FTIR) study, total flavonoid content and anti-tyrosinase activity of leaf, seed and flesh extracts of Garcinia schomburgkiana and lotion formulation from the extracts were carried out. Additionally, a relationship among FTIR spectra, total flavonoid content and anti-tyrosinase activity was analysed by partial least squares structural equation modelling (PLS-SEM) and principal component analysis (PCA) analysis. The result indicated that the highest total flavonoid content was found in leaf ethanol extract (214.00 ± 7.32 mg rutin equivalent per mg extract). For lotion samples, lotion containing leaf ethanol extract revealed the strongest level of total flavonoid content (5.51 ± 0.04 mg rutin equivalent per mL lotion). Moreover, anti-tyrosinase activity was observed in lotion containing the extracts (1/EC50 ranged from 0.0063 to 7.2334) higher than that of aqueous, ethanol and propanediol extracts (1/EC50 ranged from 0.0099 to 0.5319). The FTIR result confirmed the presence of various function groups in different parts of G. schomburgkiana and lotion samples, which involved the structure of flavonoids namely O-H stretch, C=O bending vibrations, unsaturation bonds, phenol or tertiary alcohol (O-H bend), C-O-H deformation and C-O stretching vibrations of aromatic ethers. The PLS-SEM analysis indicated a moderate positive relationship between the total flavonoid content and FTIR data, significantly (β = 0.502, t = 2.239, p-value < 0.05). The FTIR and subsequent PCA analysis could differentiate of aqueous, ethanol and propanediol extracts and lotion samples. © 2022, Walailak University. All rights reserved.