Publication: An efficacy and safety of nanofractional radiofrequency for the treatment of striae alba
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Issued Date
2017
Resource Type
File Type
application/pdf
ISSN
14732130
Other identifier(s)
2-s2.0-84992382905
Rights Holder(s)
มหาวิทยาลัยศรีนครินทรวิโรฒ
Bibliographic Citation
Journal of Cosmetic Dermatology. Vol 16, No.1 (2017), p.84-90
Suggested Citation
Pongsrihadulchai N., Chalermchai T., Ophaswongse S., Pongsawat S., Udompataikul M. An efficacy and safety of nanofractional radiofrequency for the treatment of striae alba. Journal of Cosmetic Dermatology. Vol 16, No.1 (2017), p.84-90. doi:10.1111/jocd.12292 Retrieved from: https://hdl.handle.net/20.500.14740/4224
Abstract
Background: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Its mechanism of action is to stimulate dermal remodeling and epidermal re-epithelization. Aim: To evaluate the efficacy and safety of nanofractional RF in the treatment of striae alba. Patients/Methods: This is an experimental, assessor-blinded, before–after study. Thirty-three subjects, with striae alba on their thighs, abdomen, or buttocks (11 subjects each) were enrolled. Treatments with nanofractional RF were undergone for a total of three sessions at 4-week intervals. Clinical outcomes were assessed, by comparing pre- and post-treatment measurement of total lesional surface area (using digital Pictzar™ software), and length and width of lesions. Histopathological evaluation was also performed. Results: At 4 weeks after the last treatment, the total surface area, and the width and the length of striae alba significantly decreased from the baseline (P < 0.001). Postinflammatory hyperpigmentation was reported in six subjects. Regarding histopathology, the average mean number of collagen and elastin bundles was significantly increased (P = 0.005 and 0.012, respectively). Conclusion: Nanofractional RF is highly effective with a good safety profile for the treatment of striae alba. © 2016 Wiley Periodicals, Inc.
Subject(s)
Collagen
Corticosteroid
Elastin
Hydroquinone
Retinoid
Abdomen
Adult
Article
Buttock
Clinical article
Clinical assessment
Epidermis
Female
Histopathology
Human
Male
Microneedle
Nanofractional radiofrequency
Prevalence
Radiofrequency
Safety
Skin scar
Stria
Striae alba
Thigh
Adverse effects
Catheter ablation
Middle aged
Pathology
Patient satisfaction
Procedures
Single blind procedure
Striae Distensae
Treatment outcome
Young adult
Abdomen
Adult
Buttocks
Catheter Ablation
Female
Humans
Male
Middle Aged
Patient Satisfaction
Single-Blind Method
Striae Distensae
Thigh
Treatment Outcome
Young Adult
Corticosteroid
Elastin
Hydroquinone
Retinoid
Abdomen
Adult
Article
Buttock
Clinical article
Clinical assessment
Epidermis
Female
Histopathology
Human
Male
Microneedle
Nanofractional radiofrequency
Prevalence
Radiofrequency
Safety
Skin scar
Stria
Striae alba
Thigh
Adverse effects
Catheter ablation
Middle aged
Pathology
Patient satisfaction
Procedures
Single blind procedure
Striae Distensae
Treatment outcome
Young adult
Abdomen
Adult
Buttocks
Catheter Ablation
Female
Humans
Male
Middle Aged
Patient Satisfaction
Single-Blind Method
Striae Distensae
Thigh
Treatment Outcome
Young Adult
