Publication: Localized periorbital edema induced by ibuprofen
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Issued Date
2005
Resource Type
File Type
application/pdf
ISSN
3852407
Other identifier(s)
2-s2.0-32944472946
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of Dermatology. Vol 32, No.12 (2005), p.969-971
Suggested Citation
Palungwachira P., Palungwachira P., Ogawa H. Localized periorbital edema induced by ibuprofen. Journal of Dermatology. Vol 32, No.12 (2005), p.969-971. doi:10.1111/j.1346-8138.2005.tb00883.x Retrieved from: https://hdl.handle.net/20.500.14740/6183
Author(s)
Abstract
We documented localized periorbital edema in one patient with ibuprofen sensitivity without underlying chronic urticaria. The reaction developed one hour after ingestion of 200 mg of ibuprofen. No systemic symptoms were observed. No other NSAIDs did not induce symptoms. This patient was able to tolerate doses of ibuprofen after pretreatment with terfenadine. These observations suggest that histamine played a central role in this ibuprofen-induced skin reaction. Treatment with terfenadine enabled the patient to tolerate ibuprofen without experiencing any side effects. To the best of our knowledge, this is the first reported case of periorbital edema induced by ibuprofen.