Publication: Parathyroid carcinoma
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Issued Date
2021
Resource Type
Language
eng
File Type
application/pdf
ISSN
1252208
Other identifier(s)
2-s2.0-85116009372
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S83-S90
Suggested Citation
Wongwattana P., Wiriyaamornchai P. Parathyroid carcinoma. Journal of the Medical Association of Thailand. Vol 104, No.9 (2021), p.S83-S90. doi:10.35755/jmedassocthai.2021.S03.00004 Retrieved from: https://hdl.handle.net/20.500.14740/3872
Author(s)
Abstract
Parathyroid carcinoma is a very rare cancer, accounting for 0.5% to 5% of all causes of primary hyperparathyroidism. Parathyroid carcinoma has an equal frequency of occurrence in both genders, usually in the fifth decade of life. Preoperative diagnosis of parathyroid carcinoma is difficult due to a lack of clinical findings, laboratory results, or radiological characteristics specific to the disease. Though, parathyroid carcinoma patients usually present with severe hypercalcemia at the time of diagnosis. Complete en-bloc resection is the mainstay of the treatment. The adjuvant therapy such as radiotherapy or chemotherapy has not shown effective in the treatment of parathyroid carcinoma. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND, 2021.
Subject(s)
Alkaline phosphatase
Bisphosphonic acid derivative
Calcitonin
Dacarbazine
Denosumab
Doxorubicin
Fluorouracil
Lomustine
Methotrexate
Methoxy isobutyl isonitrile technetium tc 99m
Sorafenib
Adjuvant therapy
Akt/mTOR signaling
Anorexia
Cancer staging
Cell proliferation
Computer assisted tomography
Data base
Disease classification
Distant metastasis
Echography
En bloc resection
End stage renal disease
Environmental factor
Fine needle aspiration biopsy
Gene mutation
Histology
Histopathology
Human
Hypercalcemia
Hyperparathyroidism
Hypoparathyroidism
Immunohistochemistry
Jaw tumor
Lung metastasis
Lymph node metastasis
Monotherapy
Morbidity
Nuclear magnetic resonance imaging
Parathyroid adenoma
Parathyroid carcinoma
Parathyroid hyperplasia
Pathogenesis
Pathology
Polydipsia
Polyuria
Positron emission tomography
Positron emission tomography-computed tomography
Review
Scintigraphy
Treatment response
Tumor invasion
Tumor suppressor gene
Tumor volume
Vomiting
Weakness
Bisphosphonic acid derivative
Calcitonin
Dacarbazine
Denosumab
Doxorubicin
Fluorouracil
Lomustine
Methotrexate
Methoxy isobutyl isonitrile technetium tc 99m
Sorafenib
Adjuvant therapy
Akt/mTOR signaling
Anorexia
Cancer staging
Cell proliferation
Computer assisted tomography
Data base
Disease classification
Distant metastasis
Echography
En bloc resection
End stage renal disease
Environmental factor
Fine needle aspiration biopsy
Gene mutation
Histology
Histopathology
Human
Hypercalcemia
Hyperparathyroidism
Hypoparathyroidism
Immunohistochemistry
Jaw tumor
Lung metastasis
Lymph node metastasis
Monotherapy
Morbidity
Nuclear magnetic resonance imaging
Parathyroid adenoma
Parathyroid carcinoma
Parathyroid hyperplasia
Pathogenesis
Pathology
Polydipsia
Polyuria
Positron emission tomography
Positron emission tomography-computed tomography
Review
Scintigraphy
Treatment response
Tumor invasion
Tumor suppressor gene
Tumor volume
Vomiting
Weakness