Publication:
Comparative trial of moisturizer containing spent grain wax, Butyrospermum parkii Extract, Argania spinosa kernel oil vs. 1% hydrocortisone cream in the treatment of childhood atopic dermatitis

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Issued Date

2014

Resource Type

Article

File Type

application/pdf

ISSN

1252208

Other identifier(s)

2-s2.0-84908606837

Rights Holder(s)

Scopus

Bibliographic Citation

Journal of the Medical Association of Thailand. Vol 97, No.8 (2014), p.820-826

Suggested Citation

Jirabundansuk P., Ophaswongse S., Udompataikul M. Comparative trial of moisturizer containing spent grain wax, Butyrospermum parkii Extract, Argania spinosa kernel oil vs. 1% hydrocortisone cream in the treatment of childhood atopic dermatitis. Journal of the Medical Association of Thailand. Vol 97, No.8 (2014), p.820-826. Retrieved from: https://hdl.handle.net/20.500.14740/6520

Title

Comparative trial of moisturizer containing spent grain wax, Butyrospermum parkii Extract, Argania spinosa kernel oil vs. 1% hydrocortisone cream in the treatment of childhood atopic dermatitis

Author(s)

Jirabundansuk P.
 Ophaswongse S.
 Udompataikul M.

Abstract

Objective: To compare an efficacy of a moisturizer containing spent grain wax, Butyrospermum parkii extract, Argania spinosa kernel oil (S) with 1% hydrocortisone cream (HC) for the treatment of mild to moderate atopic dermatitis.Material and Method: Twenty-nine patients, age between 2 and 15 years old with mild to moderate atopic dermatitis were enrolled. The body was randomly divided to left and right side. One side was applied with S cream and the other side was applied with HC cream twice daily for four weeks. Observation of recurrence rate after remission was recorded. Clinical outcomes were analyzed by using the scoring of Atopic Dermatitis (SCORAD) score. Statistical analysis was done by using descriptive statistics, pair t-test, one-way repeated ANOVA, and McNemar’s test.Results: It was demonstrated that both agents had improvement of SCORAD score after two weeks, with statistically significant difference (p<0.001). At fourth week, both agents had improvement of SCORAD score without being statistically significant different (p>0.05). Although the S cream side had higher remission rate than the HC cream side, there was no statistically significant difference (p>0.05).Conclusion: S cream was as effective as HC cream in the treatment and maintenance period of mild to moderate childhood atopic dermatitis. © 2014 Medical Association of Thailand. All rights reserved.

Subject(s)

Argania spinosa kernel oil
 Butyrospermum parkii extract
 Dermatological agent
 Hydrocortisone
 Plant extract
 Plant medicinal product
 Spent grain wax
 Unclassified drug
 Wax
 Hydrocortisone
 Hydrocortisone acetate
 Adolescent
 Article
 Atopic dermatitis
 Child
 Clinical article
 Controlled study
 Disease severity
 Drug efficacy
 Dry skin
 Edema
 Erythema
 Excoriation
 Female
 Follow up
 Human
 Lichenoid eruption
 Male
 Outcome assessment
 Patient satisfaction
 Randomized controlled trial
 Relapse
 Remission
 Scoring of Atopic Dermatitis
 Scoring system
 Skin injury
 Analogs and derivatives
 Cereal
 Chemistry
 Comparative study
 Dermatitis, Atopic
 Intradermal drug administration
 Preschool child
 Recurrent disease
 Sapotaceae
 Severity of illness index
 Single blind procedure
 Treatment outcome
 Administration, Cutaneous
 Cereals
 Child
 Child, Preschool
 Dermatitis, Atopic
 Female
 Humans
 Hydrocortisone
 Male
 Recurrence
 Sapotaceae
 Severity of Illness Index
 Single-Blind Method
 Treatment Outcome

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URI

https://hdl.handle.net/20.500.14740/6520

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Scopus: Year 1983-2021

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