Publication: Nomogram of intracranial translucency at 11 to 13 +6 gestational weeks at king chulalongkorn memorial hospital, Bangkok, Thailand
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Issued Date
2019
Resource Type
File Type
application/pdf
ISSN
1252208
Other identifier(s)
2-s2.0-85062906466
Rights Holder(s)
Scopus
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol 102, No.2 (2019), p.178-184
Suggested Citation
Suksamarnwong M., Manotaya S. Nomogram of intracranial translucency at 11 to 13 +6 gestational weeks at king chulalongkorn memorial hospital, Bangkok, Thailand. Journal of the Medical Association of Thailand. Vol 102, No.2 (2019), p.178-184. Retrieved from: https://hdl.handle.net/20.500.14740/5464
Author(s)
Abstract
Objective: To create a nomogram of intracranial translucency (IT) and to study the correlation between IT and crown-rump length (CRL), and between IT and gestational age (GA). Materials and Methods: Thai singleton pregnant women between 11 to 13 +6 weeks of gestation were enrolled. Fetal CRL, IT, biparietal diameter (BPD), brain stem diameter (BS), brain stem to occipital bone diameter (BSOB) and cisterna magna width (CM) were measured. Best fit equations between IT and CRL, and IT and GA were constructed. The correlation between CRL and remaining parameters were calculated. Results: Two hundred eleven Thai pregnant women were enrolled. The mean GA was 12 +3 weeks (SD 5 days). The IT ranged from 0.91 to 3.89 mm (SD 0.56). Curve estimation analysis demonstrated a quadratic relationship between IT and CRL [IT (mm) = 1.928701 – 0.027603*CRL + 0.000468*CRL² (R2=0.352, p<0.001)]. A quadratic relationship also provided the best fit between IT and GA [IT (mm) = 18.242997 – 0.425972*day + 0.002744*days² (R2=0.295, p<0.001)]. Conclusion: A nomogram of IT and other intracranial structures for open spina bifida screening at 11 to 13 +6 weeks of gestation in Thai population has been established. The assessment of IT is feasible. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND.
Subject(s)
Adult
Anthropometric parameters
Article
Biparietal distance
Brain size
Brain stem diameter
Brain stem to occipital bone diameter
Cisterna magna width
Clinical article
Echography
Female
Fetus
Fetus death
Fetus echography
Fetus weight
Gestation period
Gestational age
Human
Intracranial translucency
Middle aged
Multiple pregnancy
Open spina bifida screening
Pilot study
Pregnancy
Screening
Ultrasound
Anthropometric parameters
Article
Biparietal distance
Brain size
Brain stem diameter
Brain stem to occipital bone diameter
Cisterna magna width
Clinical article
Echography
Female
Fetus
Fetus death
Fetus echography
Fetus weight
Gestation period
Gestational age
Human
Intracranial translucency
Middle aged
Multiple pregnancy
Open spina bifida screening
Pilot study
Pregnancy
Screening
Ultrasound