Publication:
Plasmolipin, PmPLP1, from Penaeus monodon is a potential receptor for yellow head virus infection

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Issued Date

2018

Resource Type

Article

File Type

application/pdf

ISSN

0145305X

DOI

10.1016/j.dci.2018.07.021

Other identifier(s)

2-s2.0-85053082050

Rights Holder(s)

Scopus

Bibliographic Citation

Developmental and Comparative Immunology. Vol 88, (2018), p.137-143

Suggested Citation

Matjank W., Ponprateep S., Rimphanitchayakit V., Tassanakajon A., Somboonwiwat K., Vatanavicharn T. Plasmolipin, PmPLP1, from Penaeus monodon is a potential receptor for yellow head virus infection. Developmental and Comparative Immunology. Vol 88, (2018), p.137-143. doi:10.1016/j.dci.2018.07.021 Retrieved from: https://hdl.handle.net/20.500.14740/5806

Title

Plasmolipin, PmPLP1, from Penaeus monodon is a potential receptor for yellow head virus infection

Author(s)

Matjank W.
 Ponprateep S.
 Rimphanitchayakit V.
 Tassanakajon A.
 Somboonwiwat K.
 Vatanavicharn T.

Abstract

Plasmolipin has been characterized as a cell entry receptor for mouse endogenous retrovirus. In black tiger shrimp, two isoforms of plasmolipin genes, PmPLP1 and PmPLP2, have been identified from the Penaeus monodon EST database. The PmPLP1 is highly up-regulated in yellow head virus (YHV)-infected shrimp. Herein, the function of PmPLP1 is shown to be involved in YHV infection. The immunoblotting and immunolocalization showed that the PmPLP1 protein was highly expressed and located at the plasma membrane of gills from YHV-infected shrimp. Moreover, the PmPLP1 expressed in the Sf9 insect cells resided at the cell membrane rendering the cells more susceptible to YHV infection. Using the ELISA binding and mortality assays, the synthetic external loop of PmPLP1 was shown to bind the purified YHV and neutralize the virus resulting in the decrease in YHV infection. Our results suggested that the PmPLP1 was likely a receptor of YHV in shrimp. © 2018 Elsevier Ltd

Subject(s)

Protein plasmolipin
 Protein PLP1
 Proteolipid protein
 Unclassified drug
 Arthropod protein
 Myelin and lymphocyte protein
 Protein binding
 Article
 Cell membrane
 Controlled study
 Disease predisposition
 Enzyme linked immunosorbent assay
 Immunoblotting
 Immunolocalization
 Mortality rate
 Nonhuman
 Penaeus monodon
 Priority journal
 Protein expression
 Protein function
 Sf9 cell line
 Virus neutralization
 Virus purification
 Yellow head virus
 Animal
 Blood cell
 Cytology
 Gill
 Immunology
 Metabolism
 Nidovirales infection
 Penaeidae
 Roniviridae
 Spodoptera
 Upregulation
 Veterinary medicine
 Virology
 Animals
 Arthropod Proteins
 Cell Membrane
 Gills
 Hemocytes
 Myelin and Lymphocyte-Associated Proteolipid Proteins
 Nidovirales Infections
 Penaeidae
 Protein Binding
 Roniviridae
 Sf9 Cells
 Spodoptera
 Up-Regulation

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URI

https://hdl.handle.net/20.500.14740/5806

Collections

Scopus: Year 1983-2021

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