Publication:
Outcome and management of uterine leiomyosarcoma treated following surgery for presumed benign disease: Review of literature

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Issued Date

2018

Resource Type

Review

File Type

application/pdf

ISSN

22133070

DOI

10.4103/GMIT.GMIT-10-18

Other identifier(s)

2-s2.0-85046877592

Rights Holder(s)

มหาวิทยาลัยศรีนครินทรวิโรฒ

Bibliographic Citation

Gynecology and Minimally Invasive Therapy. Vol 7, No.2 (2018), p.47-55

Suggested Citation

Tantitamit T., Huang K.-G., Manopunya M., Yen C.-F. Outcome and management of uterine leiomyosarcoma treated following surgery for presumed benign disease: Review of literature. Gynecology and Minimally Invasive Therapy. Vol 7, No.2 (2018), p.47-55. doi:10.4103/GMIT.GMIT-10-18 Retrieved from: https://hdl.handle.net/20.500.14740/6112

Title

Outcome and management of uterine leiomyosarcoma treated following surgery for presumed benign disease: Review of literature

Author(s)

Tantitamit T.
 Huang K.-G.
 Manopunya M.
 Yen C.-F.

Abstract

Uterine leiomyosarcoma (uLMS) is a rare and aggressive cancer, usually diagnosed incidentally at the time of myomectomy or hysterectomy. There have been concerns for several years about the fact that the inadvertent disruption of occult uLMS may have a negative impact on patient outcome. This study reviews the outcome and management of patients with a diagnosis of uLMS after surgery for presumed benign disease. We conducted a literature search in which 47 published English-language articles were obtained for evaluation. A total of 23 studies with outcomes data were included. It is evidenced that patients who underwent surgery with tumor disruption resulted in poorer outcomes compared with en bloc tumor, especially by power morcellation. The power morcellation was associated with an increased risk of recurrence, shorten time to recurrence, and upstage after re-exploration. Early re-exploration and surgical staging are appreciated for better prognosis and may alter postoperative treatment. We also updated on the incidence and preoperative evaluation to assess the risk of patient and give an effective counseling. © 2018 Gynecology and Minimally Invasive Therapy | Published by Wolters Kluwer - Medknow.

Subject(s)

CA 125 antigen
 Fluorodeoxyglucose
 Abdominal hysterectomy
 Antibody blood level
 Cancer prognosis
 Cancer risk
 Cancer staging
 Cancer survival
 Clinical effectiveness
 Color Doppler flowmetry
 Conservative treatment
 Disease marker
 Echography
 Female
 Female fertility
 Human
 Incidence
 Leiomyosarcoma
 Myomectomy
 Nuclear magnetic resonance imaging
 Outcome assessment
 Peak systolic velocity
 Positron emission tomography
 Preoperative evaluation
 Priority journal
 Recurrence risk
 Reproductive success
 Review
 Risk factor
 Salpingooophorectomy
 Survival rate
 Treatment outcome
 Treatment response
 Tumor volume
 Ultrasound
 Uterine leiomyosarcoma
 Uterus disease
 Uterus sarcoma
 Uterus weight

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URI

https://hdl.handle.net/20.500.14740/6112

Collections

Scopus: Year 1983-2021

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Review

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